Portal Vein Thrombosis: Thrombectomy as a Treatment Option

Purpose: Portal vein thrombosis (PVT) remains a significant clinical challenge with limited treatment options, particularly in patients at high risk of hemorrhage or intestinal infarction. In such cases, mechanical thrombectomy (MT) and catheter-directed thrombolysis (CDT), either as alternative treatments or in combination with systemic anticoagulation, may provide a more suitable approach.Case Report: Here, we present 3 cases of symptomatic acute/subacute PVT with concurrent mesenteric vein thrombosis, in which patients underwent MT and CDT. The procedures were technically successful in all cases, and patients were discharged without complications.Conclusion: In this report, we give recognition to the key effect that the endovascular intervention had on the treatment of 3 different patients with PVT, highlighting the value that the endovascular approach may add to the therapeutic armamentarium and further supporting its inclusion in current treatment guidelines.Clinical Impact This study demonstrates the potential of endovascular interventions, such as MT and CDT, in treating PVT of high-risk patients. It offers a viable alternative to conventional treatments, enhancing clinical outcomes and supporting the inclusion of these techniques in updated treatment guidelines for PVT.