LYMPHOCYTE SENSITIVITY TO GLUCOCORTICOIDS

被引：10

作者：

BENEZRA, D ^{[1
]}

TICHO, U ^{[1
]}

SACHS, U ^{[1
]}

机构：

[1] HADASSAH HEBREW UNIV HOSP, DEPT OPHTHALMOL, JERUSALEM, ISRAEL

来源：

AMERICAN JOURNAL OF OPHTHALMOLOGY | 1976年 / 82卷 / 06期

关键词：

D O I：

10.1016/0002-9394(76)90062-3

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

The possibility of identifying patients with open-angle glaucoma based on the in vitro behavior of their lymphocytes in the presence of glucocorticoids was evaluated. The results did not support the hypothesis that lymphocytes from patients with open-angle glaucoma, as compared to those from normal subjects, were more sensitive to the presence of corticosteroids in vitro. The degree of inhibition induced by glucocorticoids was closely related to the amount of activation of the lymphocyte membrane induced by different concentrations of phytohemagglutinin. The results indicated that this may be a general phenomenon rather than specific to a particular ophthalmological condition.

引用

页码：866 / 870

页数：5

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