Honeybee Venom: A Potential Source of Anticancer Components

被引:0
作者
Khor, Sabrina Xin Yi [1 ]
Khongphinitbunjong, Kitiphong [2 ]
Owatworakit, Amorn [2 ,3 ]
Mah, Siau Hui [1 ,4 ]
Tang, Yin-Quan [1 ,4 ]
机构
[1] Taylors Univ, Fac Hlth & Med Sci, Sch Biosci, Subang Jaya 47500, Selangor Darul, Malaysia
[2] Mae Fah Luang Univ, Sch Sci, Chiang Rai 57100, Thailand
[3] Mae Fah Luang Univ, Microbial Prod & Innovat Res Grp, Chiang Rai 57100, Thailand
[4] Taylors Univ, Digital Hlth & Med Adv Impact Lab, Subang Jaya 47500, Selangor Darul, Malaysia
关键词
Cancer; bee venom; apitherapy; anticancer; peptides; tumor selectivity; CELL-CYCLE ARREST; BEE VENOM; CANCER CELLS; MELITTIN; SUPPRESSION; INHIBITION; ACTIVATION; APOPTOSIS; CHANNELS;
D O I
10.2174/0109298665339355241008104141
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Cancer is a deadly disease that has claimed millions of lives worldwide. Traditional cancer treatments, such as chemotherapy and radiation, have been used for many years but have become less favored due to drug resistance, lack of tumor selectivity, high costs, and various side effects, such as fatigue and hair loss. Many studies have reported that animal venoms, such as those from snakes, scorpions, and bees, contain bioactive peptides that can be synthesized into anti-cancer peptides (ACPs), which offer a potential alternative to traditional cancer therapies. Apitherapy is an area of growing interest for the development of new cancer treatments using bee venom, which is a complex mixture of biologically active peptides, enzymes, bioactive amines, and non-peptide components that have been found to have anti-cancer properties. By leveraging these bioactive peptides, researchers could develop ACPs that are more targeted towards cancer cells, reducing the risk of adverse side effects and improving patient outcomes. The use of bee venom components in targeting cancer could provide a more selective, effective, and affordable approach to cancer therapy. While further research is needed, the potential benefits of using bee venom components in cancer therapy are significant and could help improve the lives of cancer patients worldwide. This study aims to review the components of bee venom as potential cancer treatments.
引用
收藏
页码:796 / 805
页数:10
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