Exploring the Therapeutic Potential of Medicinal Plants in the Context of Gastrointestinal Health: A Review

被引：0
作者：
Julian-Flores, Antonio [1 ]
Aguilar-Zarate, Pedro [2 ]
Michel, Mariela R. [2 ]
Sepulveda-Torre, Leonardo [1 ]
Torres-Leon, Cristian [3 ]
Aguilar, Cristobal N. [1 ]
Chavez-Gonzalez, Monica L. [1 ]
机构：
[1] Autonomous Univ Coahuila, Sch Chem, Food Res Dept, Bioproc & Bioprod Grp, Saltillo 25280, Coahuila, Mexico
[2] Tecnol Nacl Mexico IT Ciudad Valles, Unidad Serv, Lab Nacl CONAHCYT Apoyo Evaluac Prod Biot LaNAEPBi, Ciudad Valles 79010, San Luis Potosi, Mexico
[3] Autonomous Univ Coahuila, Res Ctr & Ethnobiol Garden, Viesca 27480, Coahuila, Mexico
来源：
PLANTS-BASEL | 2025年 / 14卷 / 05期
关键词：
gastrointestinal diseases; intestinal microbiota; medicinal plants; bioactive compounds; IN-VITRO; GUT MICROBIOME; ANTIOXIDANT; EXTRACTS; DIGESTION;
D O I：
10.3390/plants14050642
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Medicinal plants represent promising sources for the treatment of gastrointestinal disorders because of their abundance in bioactive compounds with therapeutic properties. Throughout history, various plant species have been used to alleviate digestive ailments, and studies have revealed the presence of metabolites with anti-inflammatory, antibacterial, antiviral, antiparasitic, antidiarrheal, antioxidant, and anticancer activities. The secondary metabolites responsible for these properties include alkaloids, terpenoids, and phenolic compounds, with the latter, particularly flavonoids, being the most associated with their bioactivities. Gastrointestinal diseases, such as gastritis, peptic ulcers, gastroesophageal reflux disease, inflammatory bowel disease, irritable bowel syndrome, and gastrointestinal cancer, are caused primarily by bacteria, parasites, viruses, and the consumption of raw or undercooked foods. These conditions significantly impact human health, necessitating the development of safer and more effective therapeutic alternatives. After an extensive literature review, several plant species with widespread use in the treatment of these disorders were identified, including Matricaria chamomilla, Mentha spicata, Melissa officinalis, Artemisia ludoviciana, Flourensia cernua, Phoradendron californicum, and Turnera difusa. This study revealed that the analyzed plants are rich in bioactive compounds, which confer their medicinal properties. However, many other plants commonly used to treat digestive disorders have been scarcely studied, highlighting the need for further research.
引用
收藏
页数：19
相关论文
共 115 条
  • [1] Leader G., Murray M., O'suilleabhain P.S., Maher L., Naughton K., Arndt S., White K., Traina I., Mannion A., Relationship between parent-reported gastrointestinal symptoms, sleep problems, autism spectrum disorder symptoms, and behavior problems in children and adolescents with 22q11.2 deletion syndrome, Res. Dev. Disabil, 104, (2020)
  • [2] Kang D.W., Adams J.B., Gregory A.C., Borody T., Chittick L., Fasano A., Khoruts A., Geis E., Maldonado J., McDonough-Means S., Et al., Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: An open-label study, Microbiome, 5, (2017)
  • [3] Liu J., Tan Y., Cheng H., Zhang D., Feng W., Peng C., Functions of Gut Microbiota Metabolites, Current Status and Future Perspectives, Aging Dis, 13, (2022)
  • [4] Mazzocchi S., Visaggi P., Baroni L., Plant-based diets in gastrointestinal diseases: Which evidence?, Best Pract. Res. Clin. Gastroenterol, 62–63, (2023)
  • [5] So D., Tuck C.J., Plant-based diets in gastrointestinal disorders: Something, nothing, or everything?, Lancet Gastroenterol. Hepatol, 6, (2021)
  • [6] Sharma A., Flores-Vallejo R., Cardoso-Taketa A., Villarreal M.L., Antibacterial activities of medicinal plants used in Mexican traditional medicine, J. Ethnopharmacol, 208, pp. 264-329, (2017)
  • [7] Sellami M., Slimeni O., Pokrywka A., Kuvacic G., Hayes L.D., Milic M., Padulo J., Herbal medicine for sports: A review, J. Int. Soc. Sports Nutr, 15, (2018)
  • [8] Atanasov A.G., Waltenberger B., Pferschy-Wenzig E.M., Linder T., Wawrosch C., Uhrin P., Temml V., Wang L., Schwaiger S., Heiss E.H., Et al., Discovery and resupply of pharmacologically active plant-derived natural products: A review, Biotechnol Adv, 33, pp. 1582-1614, (2015)
  • [9] Guldiken B., Ozkan G., Catalkaya G., Ceylan F.D., Yalcinkaya I.E., Capanoglu E., Phytochemicals of herbs and spices: Health versus toxicological effects, Food Chem. Toxicol, 119, pp. 37-49, (2018)
  • [10] Feng W., Liu J., Ao H., Yue S., Peng C., Targeting gut microbiota for precision medicine: Focusing on the efficacy and toxicity of drugs, Theranostics, 10, (2020)
12345678910