Exploring the "chemo"in chemoimmunotherapy for triple-negative breast cancer

被引:1
作者
Liu, Ting [1 ,2 ]
Ellisen, Leif W. [1 ,2 ,3 ]
机构
[1] Massachusetts Gen Hosp, Canc Ctr, Boston, MA 02114 USA
[2] Harvard Med Sch, Boston, MA 02115 USA
[3] Ludwig Ctr Harvard, Boston, MA 02115 USA
关键词
D O I
10.1016/j.ccell.2025.02.016
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
In this issue of Cancer Cell, Zhang et al. use single-cell RNA sequencing to compare immune cell dynamics in triple-negative breast cancers treated with the PD-L1 inhibitor atezolizumab plus paclitaxel or nab-paclitaxel. They identify distinct T cell activation patterns and highlight mast cells' role in immune activation exclusively in the nab-paclitaxel combination.
引用
收藏
页码:332 / 334
页数:3
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