Sex Differences in Procedural Characteristics and Clinical Outcomes Among Patients Undergoing Bifurcation PCI

被引：0

作者：

Ahn, Hyun Jin ^{[1
,2
]}

Bruno, Francesco

Kang, Jeehoon ^{[1
,2
]}

Hwang, Doyeon ^{[1
,2
]}

Yang, Han-Mo ^{[1
,2
]}

Han, Jung-Kyu ^{[1
,2
]}

De Luca, Leonardo ^{[4
]}

de Filippo, Ovidio ^{[3
]}

Mattesini, Alessio ^{[5
]}

Park, Kyung Woo ^{[1
,2
]}

Truffa, Alessandra ^{[6
]}

Wanha, Wojciech ^{[7
]}

Bin Song, Young ^{[8
]}

Gili, Sebastiano ^{[9
]}

Chun, Woo Jung ^{[10
]}

Helft, Gerard ^{[11
]}

Hur, Seung-Ho

Cortese, Bernardo ^{[12
,13
]}

Han, Seung Hwan ^{[14
]}

Escaned, Javier ^{[15
,16
]}

Chieffo, Alaide ^{[17
]}

Choi, Ki Hong

Gallone, Guglielmo ^{[3
]}

Doh, Joon-Hyung ^{[18
]}

De Ferrari, Gaetano ^{[3
]}

Hong, Soon-Jun ^{[19
]}

Quadri, Giorgio ^{[3
,20
]}

Nam, Chang-Wook

Gwon, Hyeon-Cheol ^{[8
]}

Kim, Hyo-Soo ^{[1
,2
]}

D'Ascenzo, Fabrizio ^{[3
]}

Koo, Bon-Kwon ^{[1
,2
]}

机构：

[1] Seoul Natl Univ Hosp, Dept Internal Med, 101 Daehak Ro, Seoul 03080, South Korea

[2] Seoul Natl Univ Hosp, Cardiovasc Ctr, 101 Daehak Ro, Seoul 03080, South Korea

[3] Citta Salute & Sci, Dept Internal Med, Turin, Italy

[4] San Camillo Forlanini Hosp, Dept Cardiosci, Rome, Italy

[5] Cardiol Interventist AOU Careggi, I-50134 Florence, Italy

[6] Cardinal Massaia Hosp, Div Cardiol, Asti, Italy

[7] Med Univ Silesia, Dept Cardiol, Katowice, Poland

[8] Sungkyunkwan Univ, Samsung Med Ctr, Dept Cardiol, Seoul, South Korea

[9] Osped Monzino, Div Cardiol, Milan, Italy

[10] Sungkyunkwan Univ, Samsung Changwon Hosp, Changwon Si, South Korea

[11] Pierre & Marie Curie Univ, Paris, France

[12] Fdn Ric & Innovaz Cardiovasc, Sci Comm, Milan, Italy

[13] DCB Acad, Milan, Italy

[14] Gachon Univ, Dept Internal Med, Gil Hosp, Incheon, South Korea

[15] Hosp Clin San Carlos, IDISSC, Madrid, Spain

[16] Univ Complutense Madrid, Madrid, Spain

[17] Osped San Raffaele, Div Cardiol, Milan, Italy

[18] Inje Univ, Ilsan Paik Hosp, Dept Internal Med, Goyang, South Korea

[19] Korea Univ, Anam Hosp, Cardiovasc Ctr, Dept Cardiol, Seoul, South Korea

[20] Osped Rivoli, Div Cardiol, Rivoli, Italy

来源：

KOREAN CIRCULATION JOURNAL | 2025年 / 55卷 / 01期

关键词：

Sex difference; Percutaneous coronary intervention; Coronary artery disease; Coronary vessels; Drug-eluting stents; PERCUTANEOUS CORONARY INTERVENTION; ACUTE MYOCARDIAL-INFARCTION; FRACTIONAL FLOW RESERVE; DIABETES-MELLITUS; WOMEN; MORTALITY; ARTERY; MEN;

D O I：

10.4070/kcj.2024.0172

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background and Objectives: The risk profiles, procedural characteristics, and clinical outcomes for women undergoing bifurcation percutaneous coronary intervention (PCI) are not well defined compared to those in men. Methods: COronary BIfurcation Stenting III (COBIS III) is a multicenter, real-world registry of 2,648 patients with bifurcation lesions treated with second-generation drug-eluting stents. We compared the angiographic and procedural characteristics and clinical outcomes based on sex. The primary outcome was 5-year target lesion failure (TLF), a composite of cardiac death, myocardial infarction, and target lesion revascularization. Results: Women (n=635, 24%) were older, had hypertension and diabetes more often, and had smaller main vessel and side branch reference diameters than men. The pre- and post-PCI angiographic percentage diameter stenoses of the main vessel and side branch were comparable between women and men. There were no differences in procedural characteristics between the sexes. Women and men had a similar risk of TLF (6.3% vs. 7.1%, p=0.63) as well as its individual components and sex was not an independent predictor of TLF. This finding was consistent in the left main and 2 stenting subgroups. Conclusions: In patients undergoing bifurcation PCI, sex was not an independent predictor of adverse outcome.

引用

页码：5 / 16

页数：12

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