Cause of postoperative mortality in patients with end-stage renal disease

被引:1
作者
Song, Sanghoon [1 ]
Cho, Chaeyeon [1 ]
Park, Sun Young [1 ]
Cho, Ho Bum [1 ]
Yoo, Jae Hwa [1 ]
Kim, Mun Gyu [1 ]
Chung, Ji Won [1 ]
Kim, Sang Ho [1 ]
机构
[1] Soonchunhyang Univ, Seoul Hosp, Dept Anesthesiol & Pain Med, 59 Daesagwan Ro, Seoul 04401, South Korea
来源
ANESTHESIA AND PAIN MEDICINE | 2022年 / 17卷 / 02期
关键词
Cause of death; End-stage renal disease; General anesthesia; Infection; CHRONIC KIDNEY-DISEASE; PERIOPERATIVE MANAGEMENT; OXIDATIVE STRESS; HIP-ARTHROPLASTY; SURGERY; INFLAMMATION; DYSFUNCTION; MORBIDITY; IMPACT;
D O I
10.17085/apm.21080
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Background: The number of patients with end-stage renal disease (ESRD) who are dependent on hemodialysis is increasing rapidly. As a result, more patients with ESRD need surgery. These patients have a significantly higher risk of postoperative death than those with normal kidney function. Therefore, this study analyzed the causes of postoperative mortality in ESRD patients undergoing surgery under general anesthesia and the risk factors for post-operative mortality. Methods: This retrospective analysis examined the mortality of ESRD patients, 20 to 80 years old, undergoing surgery under general anesthesia. We excluded patients who under-went cardiac, cancer, or emergency surgery or organ transplantation from the analysis. The primary outcome was the cause of postoperative 30-day mortality in ESRD patients. We also assessed the mortality rate and risk factors. Results: There were 2,459 eligible ESRD patients. When patients underwent multiple surgeries during the study period, only the last surgery was considered. In total, 167 patients died during the study period, including 65 within 30 days postoperatively. The cause of death was sepsis in 22 cases (33.8%) and a major cardiac event in 16 (24.6%). Atrial fibrillation, current angina, previous myocardial infarction, asthma, lower hemoglobin and albumin levels, and a larger intraoperative colloid volume were likely to increase mortality. Conclusions: Our study suggests that immunological issues have a significant role in the death of ESRD patients after general anesthesia.
引用
收藏
页码:206 / 212
页数:152
相关论文
共 30 条
[1]  
Ben-Eliyahu S, 1999, INT J CANCER, V80, P880
[2]   Mortality in patients with end-stage renal disease and the risk of returning to the operating room after common General Surgery procedures [J].
Brakoniecki, Katrina ;
Tam, Sophia ;
Chung, Paul ;
Smith, Michael ;
Alfonso, Antonio ;
Sugiyama, Gainosuke .
AMERICAN JOURNAL OF SURGERY, 2017, 213 (02) :395-398
[3]   Chronic Kidney Disease as a Coronary Artery Disease Risk Equivalent [J].
Briasoulis, Alexandrios ;
Bakris, George L. .
CURRENT CARDIOLOGY REPORTS, 2013, 15 (03)
[4]  
Cendoroglo M, 1999, J AM SOC NEPHROL, V10, P93
[5]   Mortality and Morbidity in Dialysis-Dependent Patients Undergoing Spinal Surgery Analysis of a National Administrative Database in Japan [J].
Chikuda, Hirotaka ;
Yasunaga, Hideo ;
Horiguchi, Hiromasa ;
Takeshita, Katsushi ;
Kawaguchi, Hiroshi ;
Matsuda, Shinya ;
Nakamura, Kozo .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 2012, 94A (05) :433-438
[6]   Impact of chronic kidney disease on postoperative outcome following colorectal cancer surgery [J].
Currie, A. ;
Malietzis, G. ;
Askari, A. ;
Nachiappan, S. ;
Swift, P. ;
Jenkins, J. T. ;
Faiz, O. D. ;
Kennedy, R. H. .
COLORECTAL DISEASE, 2014, 16 (11) :879-885
[7]   Postoperative Morbidity and Mortality After Elective Anterior Cervical Fusion in Patients with Chronic and End-Stage Renal Disease [J].
De la Garza Ramos, Rafael ;
Jain, Amit ;
Nakhla, Jonathan ;
Nasser, Rani ;
Puvanesarajah, Varun ;
Hassanzadeh, Hamid ;
Yassari, Reza ;
Sciubba, Daniel M. .
WORLD NEUROSURGERY, 2016, 95 :480-485
[8]   Incidence of Infection and Inhospital Mortality in Patients With Chronic Renal Failure After Total Joint Arthroplasty [J].
Erkocak, Omer F. ;
Yoo, Joanne Y. ;
Restrepo, Camilo ;
Maltenfort, Mitchell G. ;
Parvizi, Javad .
JOURNAL OF ARTHROPLASTY, 2016, 31 (11) :2437-2441
[9]   A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease [J].
Fouque, D. ;
Kalantar-Zadeh, K. ;
Kopple, J. ;
Cano, N. ;
Chauveau, P. ;
Cuppari, L. ;
Franch, H. ;
Guarnieri, G. ;
Ikizler, T. A. ;
Kaysen, G. ;
Lindholm, B. ;
Massy, Z. ;
Mitch, W. ;
Pineda, E. ;
Stenvinkel, P. ;
Trevinho-Becerra, A. ;
Wanner, C. .
KIDNEY INTERNATIONAL, 2008, 73 (04) :391-398
[10]   Association between Albuminuria, Kidney Function, and Inflammatory Biomarker Profile in CKD in CRIC [J].
Gupta, Jayanta ;
Mitra, Nandita ;
Kanetsky, Peter A. ;
Devaney, Joe ;
Wing, Maria R. ;
Reilly, Muredach ;
Shah, Vallabh O. ;
Balakrishnan, Vaidyanathapura S. ;
Guzman, Nicolas J. ;
Girndt, Matthias ;
Periera, Brian G. ;
Feldman, Harold I. ;
Kusek, John W. ;
Joffe, Marshall M. ;
Raj, Dominic S. .
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2012, 7 (12) :1938-1946