The cruciality of increasing index of suspicion for atypical Bartonella henselae in pediatric patients: A case series

被引：0

作者：

Vazquez, Victoria ^{[1
]}

Bermudez-Rivera, Lorraine ^{[2
]}

Neto, Arino ^{[3
]}

Perez, Vanessa ^{[4
]}

Cadilla, Adriana ^{[1
]}

Sande, Linette ^{[1
]}

机构：

[1] Nemours Childrens Hosp, Dept Grad Med Educ, 6535 Nemours Pkwy, Orlando, FL 32827 USA

[2] Univ Cent Florida, Coll Med, 6850 Lake Nona Blvd, Orlando, FL 32827 USA

[3] Ann & Robert H Lurie Childrens Hosp Chicago, Dept Pediat Emergency Med, 225 E Chicago Ave,Box 86, Chicago, IL 60611 USA

[4] Advent Hlth, Dept Pediat Emergency Med, 1500 SW 1st Ave, Ocala, FL 34471 USA

来源：

IDCASES | 2025年 / 40卷

关键词：

Bartonella henselae; Bartonella endocarditis; Bartonella osteomyelitis; Bartonella neuroretinitis; Bartonella encephalitis; Atypical bartonellosis; CAT-SCRATCH DISEASE;

D O I：

10.1016/j.idcr.2025.e02192

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Bartonella henselae, a gram-negative rod, is the etiologic agent of cat scratch disease, which may manifest as a self-limiting local infection or as an atypical, invasive disease. Establishing B. henselae as the causative organism can be challenging as it is a fastidious organism that does not grow on traditional media. Diagnosis is generally performed with serology, which has variable turnaround times, or microbial cell-free DNA (mcfDNA) sequencing, which has a high cost. Therefore, a high index of suspicion is necessary for timely diagnosis and management of these invasive infections. We depict a case series of nine atypical Bartonella infections in children. By highlighting these presentations, their diagnostic testing, and treatment, we emphasize the significance of an elevated index of suspicion of atypical bartonellosis for accurate diagnosis and timely antibiotic management. Our invasive Bartonella cases entail culture-negative subacute endocarditis, osteomyelitis, neuroretinitis, encephalitis, hepatosplenic disease, and lymphadenopathy with splenic involvement.

引用

页数：6

共 19 条

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