CD276 PREDICTS A POOR RESPONSE TO IMMUNE CHECKPOINT BLOCKAGE IN UROTHELIAL CARCINOMA VIA TUMOR MICROENVIRONMENT REMODELING AND TGF-B SIGNALING

被引：0

作者：

Jack, Korleski ^{[1
]}

Fabrice, Lucien-Matteoni ^{[1
]}

Jacob, Orme ^{[1
]}

Roxane, Lavoie ^{[1
]}

机构：

[1] Mayo Clin, ROCHESTER, MN USA

来源：

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS | 2025年 / 43卷 / 03期

关键词：

D O I：

10.1016/j.urolonc.2024.12.114

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

111

引用

页数：2

共 14 条

[1] Expression patterns of the immune checkpoint ligand CD276 in urothelial carcinoma
Wilhelm K. Aicher
M. Korn
L. Reitnauer
F. B. Maurer
J. Hennenlotter
P. C. Black
T. Todenhofer
J. Bedke
A. Stenzl
BMC Urology, 21
[2] Expression patterns of the immune checkpoint ligand CD276 in urothelial carcinoma
Aicher, Wilhelm K.
Korn, M.
Reitnauer, L.
Maurer, F. B.
Hennenlotter, J.
Black, P. C.
Todenhofer, T.
Bedke, J.
Stenzl, A.
BMC UROLOGY, 2021, 21 (01)
[3] CD276 Promotes an Inhibitory Tumor Microenvironment in Hepatocellular Carcinoma and is Associated with Poor Prognosis
Liu, Wen-Feng
Jiang, Qiu-Yu
Qi, Zhuo-Ran
Zhang, Feng
Tang, Wen-Qing
Wang, Hao-Qi
Dong, Ling
JOURNAL OF HEPATOCELLULAR CARCINOMA, 2024, 11 : 1357 - 1373
[4] Elevated Expression of the Immune Checkpoint Ligand CD276 (B7-H3) in Urothelial Carcinoma Cell Lines Correlates Negatively with the Cell Proliferation
Harland, Niklas
Maurer, Florian B.
Abruzzese, Tanja
Bock, Cornelia
Montes-Mojarro, Ivonne A.
Fend, Falko
Aicher, Wilhelm K.
Stenzl, Arnulf
Amend, Bastian
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (09)
[5] COMBINED MODULATION OF THE TGF-B PATHWAY AND GITR IMMUNE CHECKPOINT SIGNALING PROMOTES ANTI-TUMOR IMMUNITY IN SYNGENEIC GLIOMA MODELS
Lorizio, Daniela
Weller, Michael
Silginer, Manuela
Epstein, Alan
Roth, Patrick
NEURO-ONCOLOGY, 2021, 23 : 94 - 94
[6] TGFβ signaling activation correlates with immune-inflamed tumor microenvironment across human cancers and predicts response to immunotherapy
Xia, Jiadong
Zhang, Qijie
Luan, Jiaochen
Min, Pengxiang
Zhang, Hanjie
Chen, Gang
Ji, Chengjian
Song, Ninghong
CELL CYCLE, 2023, 22 (01) : 57 - 72
[7] Selective blockage of the innate immune checkpoint receptor CD47 on mesothelin (MSLN) positive solid tumor cells via dual targeting bispecific antibodies alters the tumor microenvironment to control tumor growth
Majocchi, Stefano
Moine, Valery
Chauchet, Xavier
Broyer, Lucile
Cons, Laura
Chatel, Laurence
Hattererer, Eric
Buatois, Vanessa
Haddouk, Hasnaa
Didelot, Gerard
Magistrelli, Giovanni
Poitevin, Yves
Ravn, Ulla
Papaioannou, Anne
Richard, Francoise
Shang, Limin
Kosco-Vilbois, Marie H.
Fischer, Nicolas
Ferlin, Walter G.
Masternak, Krzysztof
CANCER IMMUNOLOGY RESEARCH, 2019, 7 (02)
[8] The Thrombospondin-1/CD47 signaling axis serve as potential markers of immune checkpoint blockade response modulating immune cell bioenergetics in the tumor microenvironment.
Stirling, Elizabeth
Wilson, Adam
Kooshki, Mitra
Yamaleyeva, Lilya
Jin, Guanxu
Zhang, Wei
Miller, Lance
Triozzi, Pierre
Soto-Pantoja, David
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2019, 7
[9] Targeting SNORA38B attenuates tumorigenesis and sensitizes immune checkpoint blockade in non-small cell lung cancer by remodeling the tumor microenvironment via regulation of GAB2/AKT/mTOR signaling pathway
Zhuo, Yue
Li, Shujun
Hu, Wei
Zhang, Yu
Shi, Yufan
Zhang, Faxue
Zhang, Jian
Wang, Juan
Liao, Meijuan
Chen, Jiahao
Qian, Huiling
Li, Dejia
Sun, Chengcao
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 10 (05)
[10] IMMUNE CHECKPOINT B7-H4 PROMOTES CHOLANGIOCARCINOMA GROWTH VIA TGF& BETA;- INDUCED STROMAL REMODELING, UNVEILING A NOVEL TARGETABLE TUMOR-STROMA AXIS
Bramel, Emily
Facciuto, Matias
Torres-Martin, Miguel
Park, Eric
Donne, Romain
Sritharan, Ramja
Chen, Li
Ilyas, Sumera
Petitjean, Mathieu
Tocheva, Anna
Thung, Swan
Tsankov, Alexander
Lujambio, Amaia
Sia, Daniela
HEPATOLOGY, 2024, 80

← 1 2 →