Dupilumab-Induced Erythrodermic Psoriasiform Dermatitis in Chronic Actinic Dermatitis: Case Report and Innovative Treatment Approach

被引:0
作者
Khodeir, Joe [1 ]
Habre, Maya [2 ]
机构
[1] Univ Balamand, St Georges Hosp, Fac Med & Med Sci, Dept Dermatol,Univ Med Ctr, Balamand, Lebanon
[2] St George Univ Beirut, Univ Med Ctr, St Georges Hosp, Div Dermatol, Beirut, Lebanon
来源
CLINICAL CASE REPORTS | 2024年 / 12卷 / 11期
关键词
chronic actinic dermatitis; dupilumab; dupilumab-induced psoriasis; erythrodermic psoriasis; psoriasiform dermatitis;
D O I
10.1002/ccr3.9590
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The off-label use of dupilumab has proven to be an effective treatment option for severe chronic actinic dermatitis (CAD). We present the first case of CAD presenting with dupilumab-induced erythrodermic psoriasiform dermatitis. A modified, spaced dupilumab dosing regimen, combined with cyclosporine, successfully managed both conditions, offering a promising strategy for managing dupilumab adverse effects while maintaining control over chronic actinic dermatitis.
引用
收藏
页数:4
相关论文
共 13 条
  • [1] Clearance of Chronic Actinic Dermatitis With Dupilumab Therapy in Chinese Patients: A Case Series
    Ali, Kamran
    Wu, Liming
    Lou, HaiYue
    Zhong, Jianbo
    Qiu, YunMi
    Da, JiaYang
    Shan, JingPeng
    Lu, KaiNing
    [J]. FRONTIERS IN MEDICINE, 2022, 9
  • [2] Chen Xi, 2019, JAAD Case Rep, V5, P982, DOI 10.1016/j.jdcr.2019.09.017
  • [3] Reduced Elimination of Cyclosporine A in Elderly (>65 Years) Kidney Transplant Recipients
    Falck, Pal
    Asberg, Anders
    Byberg, Karen-Therese
    Bremer, Sara
    Bergan, Stein
    Reubsaet, Jan L. E.
    Midtvedt, Karsten
    [J]. TRANSPLANTATION, 2008, 86 (10) : 1379 - 1383
  • [4] Chronic actinic dermatitis developed during phototherapy for psoriasis
    Fujii, N
    Uetsu, N
    Hamakawa, M
    Futamura, S
    Okamoto, H
    Horio, T
    [J]. PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE, 2002, 18 (03) : 157 - 159
  • [5] Dupilumab-induced psoriatic erythroderma with characteristic cytokine and antimicrobial peptide expression pattern in a patient with long standing atopic dermatitis
    Gambichler, Thilo
    Reuther, Judith
    Richards, Celine
    Doerler, Martin
    [J]. INTERNATIONAL JOURNAL OF DERMATOLOGY, 2020, 59 (09) : 1160 - 1162
  • [6] Dupilumab for chronic actinic dermatitis: A case series and review of the literature
    Holmes, Zachary
    Foley, Peter
    Baker, Chris
    Daniel, Benjamin S.
    [J]. AUSTRALASIAN JOURNAL OF DERMATOLOGY, 2024, 65 (03) : 287 - 291
  • [7] Current Status of Adverse Event Profile of Cyclosporine in Kidney, Stem Cell, and Heart Transplantations Using the Japanese Pharmacovigilance Database
    Niinomi, Iku
    Oyama, Saki
    Inada, Ayaka
    Wakabayashi, Tomohito
    Iida, Tatsuya
    Kambara, Hiroko
    Uchida, Mayako
    Sano, Yukako
    Hosohata, Keiko
    [J]. CUREUS JOURNAL OF MEDICAL SCIENCE, 2022, 14 (09)
  • [8] The coexistence of photosensitive psoriasis with chronic actinic dermatitis
    Sahoo, B
    Kumar, B
    [J]. DERMATOLOGY, 2002, 204 (01) : 77 - 79
  • [9] Targeted Treatment for Erythrodermic Psoriasis: Rationale and Recent Advances
    Shao, Shuai
    Wang, Gang
    Maverakis, Emanual
    Gudjonsson, Johann E.
    [J]. DRUGS, 2020, 80 (06) : 525 - 534
  • [10] Dupilumab-associated psoriasis and psoriasiform manifestations: a scoping review
    Su, Zheng
    Zeng, Yue-Ping
    [J]. DERMATOLOGY, 2023, 239 (04) : 646 - 657