Inhibition of MNK-eIF4E mRNA Translational Control Protects Against ERK-Mediated Retinal Ganglion Cell Degeneration

被引：0
|
作者：
Sivak, Jeremy M. [1 ,2 ]
Tuccitto, Alessandra [1 ,2 ]
Luke, Margaret [1 ,2 ]
Wigg, Karen [1 ,2 ]
机构：
[1] Univ Toronto, Toronto, ON, Canada
[2] Univ Hlth Network, Toronto, ON, Canada
来源：
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE | 2024年 / 65卷 / 07期
关键词：
D O I：
暂无
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
引用
收藏
页数：2
相关论文
共 6 条
  • [1] MNK1 Inhibition Protects Retinal Ganglion Cells From ERK Mediated Injury
    Tuccitto, Alessandra
    Guo, Xiaoxin
    Sivak, Jeremy M.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2018, 59 (09)
  • [2] TLR4 Inhibition Protects against Retinal Ganglion Cell Damage in Rats with Chronic Ocular Hypertension
    Lin, Zhongjing
    Ru, Li
    Wang, Hongliang
    Mao, Ke
    DISCOVERY MEDICINE, 2023, 35 (178) : 796 - 804
  • [3] A new paradigm for translational control:: Inhibition via 5′-3′ mRNA tethering by Bicoid and the eIF4E cognate 4EHP
    Cho, PF
    Poulin, F
    Cho-Park, YA
    Cho-Park, IB
    Chicoine, JD
    Lasko, P
    Sonenberg, N
    CELL, 2005, 121 (03) : 411 - 423
  • [4] Spatial and temporal translational control of germ cell mRNAs mediated by the eIF4E isoform IFE-1
    Friday, Andrew J.
    Henderson, Melissa A.
    Morrison, J. Kaitlin
    Hoffman, Jenna L.
    Keiper, Brett D.
    JOURNAL OF CELL SCIENCE, 2015, 128 (24) : 4487 - 4498
  • [5] Inhibition of the phosphorylation of the translational repressor 4E-BP1 without influencing the mRNA cap binding protein eIF4E. A new approach to investigate translational control in bovine oocytes
    Mayer, S.
    Tomek, W.
    REPRODUCTION IN DOMESTIC ANIMALS, 2014, 49 : 31 - 31
  • [6] Decreasing expression of Prohibitin-2 lowers the oncogenicity of renal cell carcinoma cells by suppressing eIF4E-mediated oncogene translation via MNK inhibition
    Yang, Jie
    Li, Gang
    Huang, Yue'e
    Liu, Ying
    TOXICOLOGY AND APPLIED PHARMACOLOGY, 2023, 466
1