Microbubble technology is promising for intensifying gas-liquid mass transfer in the bubble column reactor (BCR). The HiGee microbubble generator (HMG), flexibly controlling the microbubble size by adjusting the rotational speed, was developed for the BCR with obvious advantages. However, the hydrodynamics and mass transfer performance of the microbubble swarm generated by HMG in the bubble column were not clear, which hinders its industrial application process. In this work, a HiGee-aided bubble column reactor (HBCR), including an HMG and a bubble column, was proposed and designed. The effects of operating conditions on flow behavior, Sauter mean diameter (d(32)), and gas holdup (phi(G)) were studied. A prediction model for gas holdup was established, and the deviation between the predicted and experimental values was within +/- 15%. Based on d(32) and phi(G), the effective interfacial area in HBCR was calculated as 500-3800 m(2)/m(3). This study provided fundamental data for the design and scale-up of HBCR.