Guideline for the Prevention and Treatment of Metabolic Dysfunction-associated Fatty Liver Disease (Version 2024)

被引:31
作者
Fan, Jian-Gao [1 ]
Xu, Xiao-Yuan [2 ]
Yang, Rui-Xu [1 ]
Nan, Yue-Min [3 ]
Wei, Lai [4 ]
Jia, Ji-Dong [5 ]
Zhuang, Hui [6 ,7 ]
Shi, Jun-Ping [8 ]
Li, Xiao-Ying [9 ]
Sun, Chao [1 ]
Li, Jie [10 ]
Wong, Vincent Wai-Sun [11 ]
Duan, Zhong-Ping [12 ]
机构
[1] Shanghai Jiao Tong Univ, Xinhua Hosp, Sch Med, Dept Gastroenterol, 1665 Kongjiang Rd, Shanghai 200092, Peoples R China
[2] Peking Univ First Hosp, Dept Infect Dis, Beijing, Peoples R China
[3] Hebei Med Univ, Hosp 3, Dept Tradit & Western Med Hepatol, 139 Ziqiang Rd, Shijiazhuang 050051, Hebei, Peoples R China
[4] Tsinghua Univ, Beijing Tsinghua Changgung Hosp, Hepatopancreatobiliary Ctr, 168 Litang Rd, Beijing 102218, Peoples R China
[5] Capital Med Univ, Beijing Friendship Hosp, Liver Res Ctr, Beijing, Peoples R China
[6] Peking Univ Hlth Sci Ctr, Dept Microbiol, Beijing, Peoples R China
[7] Peking Univ Hlth Sci Ctr, Ctr Infect Dis, Beijing, Peoples R China
[8] Hangzhou Normal Univ, Affiliated Hosp, Dept Hepatol, Hangzhou, Zhejiang, Peoples R China
[9] Fudan Univ, Zhongshan Hosp, Dept Endocrinol & Metab, Shanghai, Peoples R China
[10] Nanjing Univ, Nanjing Drum Tower Hosp, Affiliated Hosp, Med Sch, Nanjing, Jiangsu, Peoples R China
[11] Chinese Univ Hong Kong, Inst Digest Dis, State Key Lab Digest Dis, Hong Kong, Peoples R China
[12] Capital Med Univ, Beijing Youan Hosp, Dept Liver Dis 4, Beijing, Peoples R China
关键词
Quality of evidence; Non-alcoholic fatty liver disease; Metabolic dysfunction-associated fatty liver disease; Metabolic dysfunction-associated steatotic liver disease; Type 2 diabetes mellitus; Cardiovascular disease; Management; Guideline; NONALCOHOLIC STEATOHEPATITIS; CONTROLLED-TRIAL; NONINVASIVE TESTS; RISK; MANAGEMENT; STATEMENT; PREVALENCE; CIRRHOSIS; SEVERITY; FIBROSIS;
D O I
10.14218/JCTH.2024.00311
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
With the rising epidemic of obesity, metabolic syndrome, and type 2 diabetes mellitus in China, metabolic dysfunctionassociated non-alcoholic fatty liver disease has become the most prevalent chronic liver disease. This condition frequently occurs in Chinese patients with alcoholic liver disease and chronic hepatitis B. To address the impending public health crisis of non-alcoholic fatty liver disease and its underlying metabolic issues, the Chinese Society of Hepatology and the Chinese Medical Association convened a panel of clinical experts to revise and update the "Guideline of prevention and treatment of non-alcoholic fatty liver disease (2018, China)". The new edition, titled "Guideline for the prevention and treatment of metabolic dysfunction-associated fatty liver disease (Version 2024)", offers comprehensive recommendations on key clinical issues, including screening and monitoring, diagnosis and evaluation, treatment, and followup for metabolic dysfunction-associated fatty liver disease and metabolic dysfunction-associated steatotic liver disease. Metabolic dysfunction-associated fatty liver disease the preferred English term and is used interchangeably metabolic dysfunction-associated steatotic liver disease. ditionally, the guideline emphasizes the importance of tidisciplinary collaboration among hepatologists and specialists to manage cardiometabolic disorders and disease effectively. Citation of this article: Fan JG, Xu XY, Yang RX, Nan Wei L, Jia JD, et al . Guideline for the Prevention and ment of Metabolic Dysfunction-associated Fatty Liver Disease (Version 2024). J Clin Transl Hepatol 2024. doi: 10.14218/ JCTH.2024.00311.
引用
收藏
页码:955 / 974
页数:20
相关论文
共 175 条
[61]   Global incidence of non-alcoholic fatty liver disease: A systematic review and meta-analysis of 63 studies and 1,201,807 persons [J].
Le, Michael H. ;
Le, David M. ;
Baez, Thomas C. ;
Wu, Yuankai ;
Ito, Takanori ;
Lee, Eunice Y. ;
Lee, KeeSeok ;
Stave, Christopher D. ;
Henry, Linda ;
Barnett, Scott D. ;
Cheung, Ramsey ;
Nguyen, Mindie H. .
JOURNAL OF HEPATOLOGY, 2023, 79 (02) :287-295
[62]   Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial [J].
Lean, Michael E. J. ;
Leslie, Wilma S. ;
Barnes, Alison C. ;
Brosnahan, Naomi ;
Thom, George ;
McCombie, Louise ;
Peters, Carl ;
Zhyzhneuskaya, Sviatlana ;
Al-Mrabeh, Ahmad ;
Hollingsworth, Kieren G. ;
Rodrigues, Angela M. ;
Rehackova, Lucia ;
Adamson, Ashley J. ;
Sniehotta, Falko F. ;
Mathers, John C. ;
Ross, Hazel M. ;
McIlvenna, Yvonne ;
Stefanetti, Renae ;
Trenell, Michael ;
Welsh, Paul ;
Kean, Sharon ;
Ford, Ian ;
McConnachie, Alex ;
Sattar, Naveed ;
Taylor, Roy .
LANCET, 2018, 391 (10120) :541-551
[63]  
Ledford Heidi, 2024, Nature, DOI 10.1038/d41586-024-00747-9
[64]   Low liver fat in non-alcoholic steatohepatitis-related significant fibrosis and cirrhosis is associated with hepatocellular carcinoma, decompensation and mortality [J].
Lee, Sung Won ;
Huang, Daniel Q. ;
Bettencourt, Ricki ;
Ajmera, Veeral ;
Tincopa, Monica ;
Noureddin, Nabil ;
Amangurbanova, Maral ;
Siddiqi, Harris ;
Madamba, Egbert ;
Majzoub, Abdul M. ;
Nayfeh, Tarek ;
Tamaki, Nobuharu ;
Izumi, Namiki ;
Nakajima, Atsushi ;
Yoneda, Masato ;
Idilman, Ramzan ;
Gumussoy, Mesut ;
Oz, Digdem Kuru ;
Erden, Ayse ;
Loomba, Rohit .
ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2024, 59 (01) :80-88
[65]   Non-invasive tests of non-alcoholic fatty liver disease [J].
Li, Guanlin ;
Zhang, Xinrong ;
Lin, Huapeng ;
Liang, Lilian Yan ;
Wong, Grace Lai-Hung ;
Wong, Vincent Wai-Sun .
CHINESE MEDICAL JOURNAL, 2022, 135 (05) :532-546
[66]   An individual patient data meta-analysis to determine cut-offs for and confounders of NAFLD-fibrosis staging with magnetic resonance elastography [J].
Liang, Jia-xu ;
Ampuero, Javier ;
Niu, Hao ;
Imajo, Kento ;
Noureddin, Mazen ;
Behari, Jaideep ;
Lee, Dae Ho ;
Ehman, Richard L. ;
Rorsman, Fredrik ;
Vessby, Johan ;
Lacalle, Juan R. ;
Mozes, Ferenc E. ;
Pavlides, Michael ;
Anstee, Quentin M. ;
Harrison, Stephen A. ;
Castell, Javier ;
Loomba, Rohit ;
Romero-Gomez, Manuel .
JOURNAL OF HEPATOLOGY, 2023, 79 (03) :592-604
[67]   The effects of GLP-1 receptor agonists on visceral fat and liver ectopic fat in an adult population with or without diabetes and nonalcoholic fatty liver disease: A systematic review and meta-analysis [J].
Liao, Chao ;
Liang, Xinyin ;
Zhang, Xiao ;
Li, Yao .
PLOS ONE, 2023, 18 (08)
[68]   Vibration-Controlled Transient Elastography Scores to Predict Liver-Related Events in Steatotic Liver Disease [J].
Lin, Huapeng ;
Lee, Hye Won ;
Yip, Terry Cheuk-Fung ;
Tsochatzis, Emmanuel ;
Petta, Salvatore ;
Bugianesi, Elisabetta ;
Yoneda, Masato ;
Zheng, Ming-Hua ;
Hagstrom, Hannes ;
Boursier, Jerome ;
Calleja, Jose Luis ;
Goh, George Boon-Bee ;
Chan, Wah-Kheong ;
Gallego-Duran, Rocio ;
Sanyal, Arun J. ;
de Ledinghen, Victor ;
Newsome, Philip N. ;
Fan, Jian-Gao ;
Castera, Laurent ;
Lai, Michelle ;
Harrison, Stephen A. ;
Fournier-Poizat, Celine ;
Wong, Grace Lai-Hung ;
Pennisi, Grazia ;
Armandi, Angelo ;
Nakajima, Atsushi ;
Liu, Wen-Yue ;
Shang, Ying ;
de Saint-Loup, Marc ;
Llop, Elba ;
Teh, Kevin Kim-Jun ;
Lara-Romero, Carmen ;
Asgharpour, Amon ;
Mahgoub, Sara ;
Chan, Mandy Sau-Wai ;
Canivet, Clemence M. ;
Romero-Gomez, Manuel ;
Kim, Seung Up ;
Wong, Vincent Wai-Sun .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2024, 331 (15) :1287-1297
[69]   Efficiency of ursodeoxycholic acid for the treatment of nonalcoholic steatohepatitis: A systematic review and meta-analysis [J].
Lin, Xiaozhuan ;
Mai, Meiqing ;
He, Taiping ;
Huang, Hairong ;
Zhang, Peiwen ;
Xia, Enqin ;
Guo, Honghui .
EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY, 2022, 16 (06) :537-545
[70]   Burden of liver complications related to non-alcoholic fatty liver disease in China from 2005 to 2019: Observations from the Global Burden of Disease Study, 2019 [J].
Liu, Huixin ;
Qi, Jinlei ;
Yang, Jia ;
Liu, Feng ;
Li, Xiaohe ;
Yin, Peng ;
Wang, Lijun ;
Liang, Zhisheng ;
Wei, Lai ;
Rao, Huiying ;
Zhou, Maigeng .
DIABETES OBESITY & METABOLISM, 2023, 25 :43-52