IL-6 INDUCES THE OVEREXPRESSION OF GENES INVOLVED IN THE REGULATION OF APOPTOSIS AND CELL-CELL ADHESION IN POLARIZED COLORECTAL CANCER CELLS

被引：0

作者：

Alves, Barbara ^{[1
]}

Pereira, Joana F. ^{[1
,2
]}

Ferrao, Jose ^{[1
]}

Vieira, Luis ^{[1
,3
]}

Matos, Paulo ^{[1
,2
]}

Jordan, Peter ^{[1
,2
]}

Goncalves, Vania ^{[1
,2
]}

机构：

[1] Inst Nacl Saude Doutor Ricardo Jorge, Dept Genet Humana, P-1649016 Lisbon, Portugal

[2] Univ Lisbon, BioISI Inst Biosistemas & Ciencias Integrat, Fac Ciencias, P-1749016 Lisbon, Portugal

[3] Univ Nova Lisboa, Fac Ciencias Med, Ctr Toxicogenom & Saude Humana ToxOm, NOVA Med Sch, P-1169056 Lisbon, Portugal

来源：

MEDICINE | 2025年 / 104卷 / 04期

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

P23

引用

页数：2

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[41] IL-6 suppresses dendritic cell-mediated antitumor immunity and promotes liver metastasis of colorectal cancer cells [J].

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[49] Macrophage inhibitory cytokine 1 reduces cell adhesion and induces apoptosis in prostate cancer cells [J].

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