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Diagnostic accuracy comparison of the Fluorion MTBC QLP 2.1 real-time PCR and the COBAS TaqMan MTB assays for Mycobacterium tuberculosis detection
被引:0
作者:
Madihi, Salma
[1
]
Aainouss, Achraf
[2
]
El Messaoudi, Mly Driss
[2
]
Benani, Abdelouaheb
[1
]
机构:
[1] Inst Pasteur Maroc, Mol Biol Lab, Pl Louis Pasteur, Casablanca 20360, Morocco
[2] Inst Pasteur Maroc, Lab Mycobacteria & TB, Casablanca, Morocco
关键词:
COBAS TaqMan MTB;
Diagnosis;
Fluorion MTBC QLP 2.1 real-time PCR;
Methods comparison;
Mycobacterium tuberculosis;
D O I:
10.1016/j.mimet.2025.107115
中图分类号:
Q5 [生物化学];
学科分类号:
071010 ;
081704 ;
摘要:
The Fluorion MTBC QLP 2.1 Real-Time PCR test is a valuable alternative for tuberculosis diagnosis, demonstrating 100 % specificity and 87.5 % sensitivity for respiratory specimens, 97.8 % specificity and 85.3 sensitivity for non-respiratory specimens, and an overall agreement of 92.3 % with the COBAS TaqMan MTB assay.
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