Diagnostic accuracy comparison of the Fluorion MTBC QLP 2.1 real-time PCR and the COBAS TaqMan MTB assays for Mycobacterium tuberculosis detection

被引：0
|
作者：
Madihi, Salma [1 ]
Aainouss, Achraf [2 ]
El Messaoudi, Mly Driss [2 ]
Benani, Abdelouaheb [1 ]
机构：
[1] Inst Pasteur Maroc, Mol Biol Lab, Pl Louis Pasteur, Casablanca 20360, Morocco
[2] Inst Pasteur Maroc, Lab Mycobacteria & TB, Casablanca, Morocco
来源：
JOURNAL OF MICROBIOLOGICAL METHODS | 2025年 / 232卷
关键词：
COBAS TaqMan MTB; Diagnosis; Fluorion MTBC QLP 2.1 real-time PCR; Methods comparison; Mycobacterium tuberculosis;
D O I：
10.1016/j.mimet.2025.107115
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
The Fluorion MTBC QLP 2.1 Real-Time PCR test is a valuable alternative for tuberculosis diagnosis, demonstrating 100 % specificity and 87.5 % sensitivity for respiratory specimens, 97.8 % specificity and 85.3 sensitivity for non-respiratory specimens, and an overall agreement of 92.3 % with the COBAS TaqMan MTB assay.
引用
收藏
页数：3
相关论文
共 50 条
  • [1] Comparison of PNA probe-based real-time PCR and Cobas TaqMan MTB for detection of MTBC
    Kim, Jae Woo
    Choi, Young Jin
    Kim, Hwi Jun
    Park, Joon Soo
    Nam, Hae Seon
    Hwangbo, Young
    Kim, Doug Uk
    Park, Kwi Sung
    BIOCHIP JOURNAL, 2013, 7 (02) : 85 - 88
  • [2] Evaluation of Cobas TaqMan MTB for Direct Detection of the Mycobacterium tuberculosis Complex in Comparison with Cobas Amplicor MTB
    Bloemberg, Guido V.
    Voit, Antje
    Ritter, Claudia
    Deggim, Vanessa
    Boettger, Erik C.
    JOURNAL OF CLINICAL MICROBIOLOGY, 2013, 51 (07) : 2112 - 2117
  • [3] Comparison of AdvanSure TB/NTM PCR and COBAS TaqMan MTB PCR for Detection of Mycobacterium tuberculosis Complex in Routine Clinical Practice
    Cho, Won-Hyung
    Won, Eun-Jeong
    Choi, Hyun-Jung
    Kee, Seung-Jung
    Shin, Jong-Hee
    Ryang, Dong-Wook
    Suh, Soon-Pal
    ANNALS OF LABORATORY MEDICINE, 2015, 35 (03) : 356 - 361
  • [4] Comparison of the Xpert MTB/RIF Assay and Real-time PCR for the Detection of Mycobacterium tuberculosis
    Kim, Min Jin
    Nam, You Sun
    Cho, Sun Young
    Park, Tae Sung
    Lee, Hee Joo
    ANNALS OF CLINICAL AND LABORATORY SCIENCE, 2015, 45 (03) : 327 - 332
  • [5] Comparison of the Genedia MTB Detection Kit and the Cobas TaqMan MTB Assay for Detection of Mycobacterium tuberculosis in Respiratory Specimens
    Huh, Hee Jae
    Kwon, Hyeon Jeong
    Ki, Chang-Seok
    Lee, Nam Yong
    JOURNAL OF CLINICAL MICROBIOLOGY, 2015, 53 (03) : 1012 - 1014
  • [6] Evaluation of Point Mutation Detection in Mycobacterium tuberculosis with Isoniazid Resistance Using Real-Time PCR and TaqMan Probe Assay
    Riahi, F.
    Derakhshan, M.
    Mosavat, A.
    Soleimanpour, S.
    Rezaee, S. A.
    APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 2015, 175 (05) : 2447 - 2455
  • [7] Standardization of a TaqMan-Based Real-Time PCR for the Detection of Mycobacterium tuberculosis-Complex in Human Sputum
    Barletta, Francesca
    Vandelannoote, Koen
    Collantes, Jimena
    Evans, Carlton A.
    Arevalo, Jorge
    Rigouts, Leen
    AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2014, 91 (04) : 709 - 714
  • [8] Comparison and Evaluation of Real-Time Taqman PCR for Detection and Quantification of Ebolavirus
    Huang, Yi
    Xiao, Shuqi
    Yuan, Zhiming
    VIRUSES-BASEL, 2021, 13 (08):
  • [9] TaqMan real-time PCR versus four conventional PCR assays for detection of apple proliferation phytoplasma
    Baric, S.
    Kerschbamer, C.
    Dalla Via, J.
    PLANT MOLECULAR BIOLOGY REPORTER, 2006, 24 (02) : 169 - 184
  • [10] TaqMan real-time PCR versus four conventional PCR assays for detection of apple proliferation phytoplasma
    S. Baric
    C. Kerschbamer
    J. Dalla Via
    Plant Molecular Biology Reporter, 2006, 24
12345