Identification of near full-length human pegivirus type 2 (HPgV-2) genomes in blood donor samples co-infected with hepatitis C virus (HCV)

被引：0

作者：

Ragupathy, Viswanath ^{[1
]}

Kelley, Kylan ^{[1
]}

Hewlett, Indira ^{[1
]}

机构：

[1] FDA, Ctr Biol Evaluat & Res, Div Emerging & Transfus Transmitted Dis, Lab Mol Virol, Silver Spring, MD 20852 USA

来源：

MICROBIOLOGY RESOURCE ANNOUNCEMENTS | 2025年 / 14卷 / 03期

关键词：

pegivirus; HPgV-2; metagenomics; hepatitis C virus; nanopore; PREVALENCE;

D O I：

10.1128/mra.01179-24

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Human pegivirus (HPgV) identified from an HCV-infected plasma sample through nanopore metagenomics. The analysis revealed a nearly complete HPgV-2 genome. Phylogenetic analysis confirmed its classification within the HPgV-2 geno type, providing insights into viral co-infection dynamics. The metagenomics approach advances the understanding of viral diversity and supports the development of accurate diagnostics.

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