Advances in research on the intestinal microbiota in the mechanism and prevention of colorectal cancer (Review)

被引：0
|
作者：
Sun, Weitong [1 ]
Ma, Shize [1 ]
Meng, Dongdong [2 ]
Wang, Chaoxing [1 ]
Zhang, Jinbo [1 ]
机构：
[1] Jiamusi Univ, Coll Pharm, 258 Xuefu St, Jiamusi 154000, Heilongjiang, Peoples R China
[2] Childrens Hosp, Dept Med Serv, Xuzhou Morning Star Womens, Xuzhou 221000, Jiangsu, Peoples R China
来源：
MOLECULAR MEDICINE REPORTS | 2025年 / 31卷 / 05期
关键词：
intestinal microbiota; colorectal cancer; intestinal barrier; LACTIC-ACID BACTERIA; LACTOBACILLUS-RHAMNOSUS GG; CONJUGATED LINOLEIC-ACID; IN-VITRO; CELL-PROLIFERATION; DIETARY FIBER; PROBIOTIC BACTERIA; ESCHERICHIA-COLI; GUT MICROBIOTA; FECAL ENZYMES;
D O I：
10.3892/mmr.2025.13498
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The intestinal microbiota represents a diverse population that serves a key role in colorectal cancer (CRC) and its treatment outcomes. Advancements in sequencing have revealed notable shifts in microbial composition and diversity among individuals with CRC. Concurrently, animal models have elucidated the involvement of specific microbes such as Lactobacillus fragilis, Escherichia coli and Fusobacterium nucleatum in the progression of CRC. The present review aimed to highlight contributions of intestinal microbiota to the pathogenesis of CRC, the effects of traditional treatments on intestinal microbiota and the potential for microbiota modulation as a therapeutic strategy for CRC.
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页数：17
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