Mild behavioural impairment in Parkinson's disease: a systematic review

被引：0

作者：

Yu, Ruan-Ching ^{[1
]}

Chan, Lung ^{[2
,3
,4
]}

Chou, Szu-Yi ^{[5
,6
,7
,8
]}

Lin, Li-Fong ^{[9
,10
]}

Hu, Chaur-Jong ^{[2
,3
,4
]}

Hong, Chien-Tai ^{[2
,3
,4
]}

机构：

[1] UCL, Dept Psychiat, London, England

[2] Taipei Med Univ, Shuang Ho Hosp, Dept Neurol, New Taipei, Taiwan

[3] Taipei Med Univ, Coll Med, Sch Med, Dept Neurol, 291 Zhongzheng Rd, New Taipei City 23561, Taiwan

[4] Taipei Med Univ, Taipei Neurosci Inst, Taipei, Taiwan

[5] Taipei Med Univ, Coll Med Sci & Technol, Program Med Neurosci, Taipei 11031, Taiwan

[6] Natl Hlth Res Inst, Taipei 11031, Taiwan

[7] Taipei Med Univ, Grad Inst Neural Regenerat Med, Coll Med Sci & Technol, Taipei, Taiwan

[8] Taipei Med Univ, Coll Med Sci & Technol, Med Neurosci, Taipei, Taiwan

[9] Taipei Med Univ, Coll Nursing, Sch Gerontol & Long Term Care, Taipei, Taiwan

[10] Taipei Med Univ, Shuang Ho Hosp, Dept Phys Med & Rehabil, New Taipei, Taiwan

来源：

AGE AND AGEING | 2024年 / 53卷 / 11期

关键词：

Parkinson's disease; mild behavioural impairment; impulse dyscontrol; depression; anxiety; systematic review; older people; QUALITY-OF-LIFE; IMPULSE CONTROL DISORDERS; NEUROPSYCHIATRIC SYMPTOMS; DIAGNOSTIC-CRITERIA; DEMENTIA; DEPRESSION;

D O I：

10.1093/ageing/afae247

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Behavioural symptoms are common manifestations of Parkinson's disease (PD). Early behavioural symptoms characterisemild behavioural impairment (MBI). The prevalence and intensity of MBI in people with PD (PwP) have been studied acrossvarious cohorts. However, methodological differences have obscured our understanding of MBI in these individuals. Thissystematic review examines and synthesises findings from relevant studies, enhancing understanding of the symptoms andimplications of MBI in PD. Nine studies from five separate research institutions were identified. The conceptualisation ofMBI varied considerably, affecting the reported prevalence rates of MBI in individuals with early-stage PD. Among PwP,MBI was associated higher education and impaired cognition. Affective dysregulation and impulse control disorders wereprimary contributors to MBI; abnormal perception was least contributor. This systematic review underscores the specificcharacteristics and incidence of MBI in early-stage PD. Mood and impulse control disorders are primary concerns associatedwith MBI. Future longitudinal studies are required to clarify the progression of these symptoms and evaluate MBI's potentialas an indicator for PD-related dementia or increased dependency.

引用

页数：10