Study on Pharmacological Treatment of Impulse Control Disorders in Parkinson's Disease

被引:1
作者
Furdu-Lungut, Emilia [1 ,2 ]
Antal, Claudia [3 ]
Turcu, Suzana [4 ]
Costea, Dan-Gabriel [5 ]
Mitran, Mihai [6 ,7 ]
Mitran, Loredana [8 ]
Diaconescu, Andrei-Sebastian [9 ,10 ]
Novac, Marius-Bogdan [11 ]
Gorecki, Gabriel-Petre [12 ,13 ]
机构
[1] Titu Maiorescu Univ, Preclin Dept, Fac Med, Bucharest 031593, Romania
[2] CF2 Clin Hosp, Dept Neurol, Bucharest 011464, Romania
[3] 2gether NHS Fdn Trust Gloucestershire, Gloucester GL3 4AW, Glos, England
[4] Romanian Acad, Francisc I Rainer Inst Anthropol, Bucharest, Romania
[5] CF2 Clin Hosp, Dept Neurol, Bucharest 011464, Romania
[6] Carol Davila Univ Med & Farmacy, Rheumatol Dept, Bucharest 020021, Romania
[7] Prof Dr Panait Sirbu Clin Hosp Obstet & Gynecol, Dept Obstet & Gynecol, Bucharest 060251, Romania
[8] Elias Univ Emergency Hosp, Dept Oncol, Bucharest 011461, Romania
[9] Carol Davila Univ Med & Farmacy, Rheumatol Dept, Bucharest 020021, Romania
[10] Fundeni Clin Inst, Dept Gen Surg, Bucharest 022328, Romania
[11] Univ Med & Pharm Craiova, Dept Anesthesiol & Intens Care, Craiova 200349, Romania
[12] Titu Maiorescu Univ, Preclin Dept, Fac Med, Bucharest 031593, Romania
[13] CF2 Clin Hosp, Dept Anesthesia & Intens Care, Bucharest 011464, Romania
关键词
pharmacological treatment; Parkinson disease; impulsive control disorders; applied statistics; RISK-FACTORS; BEHAVIORS; DIAGNOSIS;
D O I
10.3390/jcm13226708
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Parkinson's disease is neurodegenerative, and additionally, a percentage higher than 60% is represented by the patients with associated psychiatric symptoms, such as anxiety disorders and depression. Due to illness itself and to therapy secondary effects, there is a high risk for these patients to develop impulse control disorders like ICDs: compulsive shopping, pathological gambling binge eating disorder, and hypersexuality. There is high interest in therapy so as to diminish, as much as possible, the associated ICD symptoms. This article presents a study on pharmacological treatment of impulse control disorders in Parkinson disease carried on a sample of patients in hospitals where the authors have their clinical work. This study was carried on for a period of 6 years and is focused on research of different treatment plans. The patients were evaluated by the Hamilton Rating Scale. Statistical analysis of the obtained data (given by the HAM-A scores) is used for data processing. All patients showed a reduction in their impulse behavior. The directions of further research development are mentioned.
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页数:10
相关论文
共 26 条
[1]   Diagnosis and Treatment of Parkinson Disease A Review [J].
Armstrong, Melissa J. ;
Okun, Michael S. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 323 (06) :548-560
[2]  
arpim, Previziune: Numarul Bolnavilor de Parkinson se va Dubla pana in Anul 2030
[3]   Iowa Gambling Task Performance in Parkinson Disease Patients with Impulse Control Disorders [J].
Biars, Julia W. ;
Johnson, Nicole L. ;
Nespeca, Michelle ;
Busch, Robyn M. ;
Kubu, Cynthia S. ;
Floden, Darlene P. .
ARCHIVES OF CLINICAL NEUROPSYCHOLOGY, 2019, 34 (03) :310-318
[4]   Mechanisms of neurodegeneration in Parkinson's disease: keep neurons in the PINK1 [J].
Brunelli, Francesco ;
Valente, Enza Maria ;
Arena, Giuseppe .
MECHANISMS OF AGEING AND DEVELOPMENT, 2020, 189
[5]   Impulse control disorders in Parkinson's disease: definition, epidemiology, risk factors, neurobiology and management [J].
Ceravolo, Roberto ;
Frosini, Daniela ;
Rossi, Carlo ;
Bonuccelli, Ubaldo .
PARKINSONISM & RELATED DISORDERS, 2009, 15 :S111-S115
[6]   Hypersexuality in Parkinson's Disease: Systematic Review and Report of 7 New Cases [J].
Codling, David ;
Shaw, Philip ;
David, Anthony S. .
MOVEMENT DISORDERS CLINICAL PRACTICE, 2015, 2 (02) :116-126
[7]   Capacity, control and responsibility in Parkinson's disease patients with impulse control disorders: Views of neurological and psychiatric experts [J].
Dawson, Andrew ;
Michael, Jordie ;
Dilkes-Frayne, Ella ;
Hall, Wayne ;
Dissanayaka, Nadeeka N. ;
Carter, Adrian .
INTERNATIONAL JOURNAL OF LAW AND PSYCHIATRY, 2019, 65
[8]   A case-control study investigating food addiction in Parkinson patients [J].
de Chazeron, Ingrid ;
Durif, F. ;
Lambert, C. ;
Chereau-Boudet, I ;
Fantini, M. L. ;
Marques, A. ;
Derost, P. ;
Debilly, B. ;
Brousse, G. ;
Boirie, Y. ;
Llorca, P. M. .
SCIENTIFIC REPORTS, 2021, 11 (01)
[9]  
Dixon M.R., 2020, Functional Analysis in Clinical Treatment (Second Edition), P479
[10]   The Emerging Evidence of the Parkinson Pandemic [J].
Dorsey, E. Ray ;
Sherer, Todd ;
Okun, Michael S. ;
Bloem, Bastiaan R. .
JOURNAL OF PARKINSONS DISEASE, 2018, 8 :S3-S8