Prognostic value of pan immune-inflammation value in patients undergoing unprotected left main coronary artery stenting

Aim: This study aimed long-term prognostic factors for percutaneous coronary intervention (PCI) in left main coronary artery (LMCA) disease, focusing on inflammatory parameters like Pan Immune-Inflammation Value (PIV) and Systemic Immune-Inflammation Index (SII). Materials & methods: This retrospective, observational study involved 121 patients receiving unprotected LMCA PCI. The study's primary end point was MACE, including all-cause death, repeat revascularization and myocardial reinfarction. Results: The PIV and SII scores emerged as independent predictors of MACE occurrence in patients undergoing PCI for unprotected LMCA disease (p:0.045,p:0.048; respectively). In addition, age, ejection fraction, creatinine, shock presentation and the residual syntax score were identified as significant independent predictors of MACE in both models. Conclusion: This study showed a significant, independent correlation between PIV, SII and MACE in patients undergoing PCI for LMCA disease, with PIV showing slightly better predictive capability than SII.