Iatrogenic cyanoacrylate glue-induced eye injuries in the pediatric population: A national multicenter retrospective descriptive study

Introduction. - Cyanoacrylate adhesives serve multiple purposes and have increasingly been used in medical settings. Among pediatric emergencies, iatrogenic cyanoacrylate glue spillage into children's eyes is a common occurrence lacking standardized management recommendations. Methods. - This retrospective multicenter study used the French national adverse event data from January 1, 1999, to July 1, 2023. Inclusion criteria included ocular cyanoacrylate glue exposure, closed eyelids, and age < 15 years. Results. - Among 20 pediatric patients studied, primary symptoms post-eyelid opening included eyelid swelling (35%), superficial keratitis (20%), and conjunctivitis (20%). Severity assessments using the Poisoning Severity Score (PSS) showed an absence of severe eye lesions. Spontaneous eyelid detachment took an average of 8.5 days. Surgical interventions in three cases exhibited limited improvement and potential iatrogenicity. Conclusion. - This study indicates a prevalent preference for conservative management approaches to iatrogenic cyanoacrylate glue spills in pediatric ocular cases in France. No severe complications were reported among observed cases. (c) 2025 The Authors. Published by Elsevier Masson SAS. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).