The Abdominal Adiposity Index (A Body Shape Index) Predicts 10-Year All-Cause Mortality in Elderly Active Non-Obese Subjects

被引:0
作者
Nunnari, Alessio [1 ,2 ]
Di Girolamo, Filippo Giorgio [2 ,3 ]
Teraz, Kaja [1 ,4 ]
Fiotti, Nicola [1 ,2 ]
Simunic, Bostjan [4 ]
Mearelli, Filippo [1 ]
Pisot, Rado [4 ]
Biolo, Gianni [1 ,2 ]
机构
[1] Univ Trieste, Dept Med Surg & Hlth Sci, Unit Internal Med, Clin Med, Str Fiume 447, I-34100 Trieste, Italy
[2] Univ Trieste, Dept Med Surg & Hlth Sci MD, Str Fiume 447, I-34100 Trieste, Italy
[3] Azienda Sanit Univ Giuliano Isontina, Cattinara Hosp, SC Assistenza Farmaceut, Str Fiume 447, I-34100 Trieste, Italy
[4] Inst Kinesiol Res, Sci & Res Ctr Koper, Garibaldijeva Ul 1, Koper 6000, Slovenia
关键词
ABSI; a body shape index; body shape; free fat mass; sarcopenia; prognostic index; elderly; mortality; OBESITY; INFLAMMATION; SARCOPENIA; ABSI; FAT;
D O I
10.3390/jcm13206155
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background/Objectives: A Body Shape Index (ABSI), which accounts for waist circumference relative to mass and height, shows a robust association with mortality risk. The present study evaluates the effectiveness of ABSI as a predictor of 10-year all-cause mortality in physically active, non-obese elderly individuals. Methods: This prospective cohort study included 159 volunteers (94 women, aged 60-80 years), recruited in the frame of the "Physical Activity and Nutrition for Great Ageing" (PANGeA) Cross-border Cooperation Program Slovenia-Italy 2007-2013, and followed for 10 years. Baseline characteristics included anthropometric measurements, bioelectrical impedance analysis, and cardiovascular fitness tests (VO2max). Statistical analyses (Cox regression, Kaplan-Meier survival) were conducted to examine the relationship between ABSI and mortality. Results: During the 10-year follow-up, 10 deaths (6.7%) were recorded. ABSI (adjusted for age, smoking, comorbidities, and therapy) was an independent predictor of mortality (hazard ratio = 4.65, p < 0.001). Higher ABSI scores were linked to reduced VO2max (r = -0.190, p = 0.017) and increased systolic blood pressure (r = 0.262, p = 0.001). An ABSI-based predictive model showed strong discriminatory power (AUROC = 0.91). Conclusions: ABSI is a reliable predictor of 10-year mortality in active, non-obese elderly individuals and may improve risk stratification in clinical practice.
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页数:18
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