Update on the pathophysiology and management of acute trauma hemorrhage and trauma-induced coagulopathy based upon viscoelastic testing

被引：1

作者：

Maegele, Marc ^{[1
,2
]}

机构：

[1] Univ Witten Herdecke UW H, Cologne Merheim Med Ctr CMMC, Dept Trauma & Orthoped Surg, Campus Cologne Merheim,Ostmerheimer St 200, D-51109 Cologne, Germany

[2] Witten Herdecke Univ, Inst Res Operat Med IFOM, Cologne, Germany

来源：

CLINICAL AND EXPERIMENTAL EMERGENCY MEDICINE | 2024年 / 11卷 / 03期

关键词：

Trauma; Bleeding; Hemorrhage; Coagulopathy; Viscoelastic testing; ROTATIONAL THROMBOELASTOMETRY; HEMOSTATIC RESUSCITATION; MORTALITY; TRANSFUSION; ASSOCIATION; GUIDELINES; CARE; THRESHOLDS; SURGERY; PLASMA;

D O I：

10.15441/ceem.24.202

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Uncontrolled hemorrhage and trauma-induced coagulopathy (TIC) are the two predominant causes of preventable death after trauma. Early control of bleeding sources and rapid detection, characterization and management of TIC have been associated with improved outcomes. However, recent surveys confirm vast heterogeneity in the clinical diagnosis and management of hemorrhage and TIC from acute trauma, even in advanced trauma centers. In addition, conventional coagulation assays, although still used frequently during the early assessment of bleeding trauma patients, have their limitations. This narrative review highlights the clinical value of rapid point-of-care viscoelastic testing for the early diagnosis and individualized goal-directed therapy in bleeding trauma patients with TIC.

引用

页码：259 / 267

页数：9

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