Role of PCSK9 inhibitors in the management of dyslipidaemia

被引:5
作者
Nair, Tiny [1 ]
机构
[1] PRS Hosp, Dept Cardiol, Trivandrum 695002, Kerala, India
关键词
PCSK9; inhibitors; Dyslipidaemia; LDL; Familial hyperlipidemia; HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA; EVOLOCUMAB AMG 145; MONOCLONAL-ANTIBODY; SAFETY; LDL; EFFICACY; TRIAL;
D O I
10.1016/j.ihj.2023.12.011
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Proprotein convertase subtilisin kexin9 (PCSK9) inhibitors are novel agents that lower LDL cholesterol and reduce cardio-vascular event rate. Being expensive, these agents are reserved for those with high risk or very high risk of CV events and with suboptimal response to statins and ezetimibe, with or without bempedoic acid or those intolerant to statins.
引用
收藏
页码:S44 / S50
页数:7
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