The Significance of an Initial Controlling Nutritional Status Score in Predicting the Functional Outcome, Complications, and Mortality in a First-Ever Ischemic Stroke

被引：3

作者：

Choi, Hyoseon ^{[1
,2
]}

Jo, Yea Jin ^{[3
]}

Sohn, Min Kyun ^{[4
]}

Lee, Jongmin ^{[5
]}

Shin, Yong-Il ^{[6
]}

Oh, Gyung-Jae ^{[7
]}

Lee, Yang-Soo ^{[8
]}

Joo, Min Cheol ^{[9
]}

Lee, So Young ^{[10
]}

Song, Min-Keun ^{[11
]}

Han, Junhee ^{[12
]}

Ahn, Jeonghoon ^{[13
]}

Lee, Young-Hoon ^{[7
]}

Kim, Yun-Hee ^{[14
]}

Chang, Won Hyuk ^{[15
,16
]}

Kim, Deog Young ^{[2
,17
]}

机构：

[1] Eulji Univ, Nowon Eulji Med Ctr, Dept Rehabil Med, Seoul 01830, South Korea

[2] Yonsei Univ, Med Coll, Dept Rehabil Med, Seoul 03722, South Korea

[3] Gachon Univ, Dept Exercise Rehabil & Welf, 191 Hambangmore Ro, Incheon 21936, South Korea

[4] Chungnam Natl Univ, Coll Med, Dept Rehabil Med, Daejeon 34134, South Korea

[5] Konkuk Univ, Dept Rehabil Med, Sch Med, Seoul 05030, South Korea

[6] Pusan Natl Univ, Sch Med, Yangsan Hosp, Dept Rehabil Med, Yangsan 50612, South Korea

[7] Wonkwang Univ, Sch Med, Dept Prevent Med, Iksan 54538, South Korea

[8] Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Rehabil Med, Daegu 41944, South Korea

[9] Wonkwang Univ, Sch Med, Dept Rehabil Med, Iksan 54538, South Korea

[10] Jeju Natl Univ, Sch Med, Dept Rehabil Med, Jeju Natl Univ Hosp, Jeju 63241, South Korea

[11] Chonnam Natl Univ, Dept Phys & Rehabil Med, Med Sch, Gwangju 61469, South Korea

[12] Hallym Univ, Data Sci Convergence Res Ctr, Div Data Sci, Chunchon 24252, South Korea

[13] Ewha Womans Univ, Dept Hlth Convergence, Seoul 03760, South Korea

[14] Sungkyunkwan Univ, Sch Med, Dept Phys & Rehabil Med, Suwon 16419, South Korea

[15] Sungkyunkwan Univ, Heart Vasc Stroke Inst, Dept Phys & Rehabil Med, Ctr Prevent & Rehabil,Sch Med, Seoul 06351, South Korea

[16] Sungkyunkwan Univ, SAIHST, Dept Med Device Management & Res, Dept Digital Hlth,Dept Hlth Sci & Technol, Seoul 06351, South Korea

[17] Yonsei Univ, Coll Med, Dept & Res Inst Rehabil Med, Seoul 03722, South Korea

来源：

NUTRIENTS | 2024年 / 16卷 / 20期

关键词：

stroke; cerebral infarction; nutritional status; functional recovery; survival; LENGTH-OF-STAY; PROGNOSTIC IMPORTANCE; IMMUNE-SYSTEM; HOSPITAL STAY; MALNUTRITION; REHABILITATION; IMPACT; RELIABILITY; INFLAMMATION; VALIDITY;

D O I：

10.3390/nu16203461

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Background and Purpose: Nutritional status can influence the outcomes and mortality of various diseases. The association between initial nutritional status and ischemic stroke outcomes, however, remains poorly understood. This study investigated whether the Controlling Nutritional Status (CONUT) score at admission could predict functional recovery, complications, and survival following an ischemic stroke. Methods: We enrolled a total of 938 patients experiencing their first acute ischemic stroke and categorized them into three groups based on their CONUT score at admission: CONUT 0-1, CONUT 2-4, and CONUT 5-12. The CONUT score was assessed using the serum albumin, total cholesterol, and lymphocyte count. We evaluated the incidence of complications during their hospital stay. Outcomes, including the Modified Rankin Scale (mRS), Functional Independence Measurement (FIM), Functional Ambulatory Classification (FAC), and mortality, were assessed at baseline, as well as at three and six months post-stroke. Results: CONUT scores were significantly associated with functional outcomes (mRS, FIM, and FAC) and mortality during the six-month follow-up period post-stroke (all p < 0.05). The CONUT 5-12 group exhibited significantly poorer improvements in mRS, FIM, and FAC scores (all p < 0.05) and a lower survival rate (p < 0.01) during the six-month follow-up compared to the CONUT 0-1 and CONUT 2-4 groups. Additionally, the incidence of pneumonia, urinary tract infections, pressure sores, falling injuries, and fractures was significantly higher in the CONUT 5-12 group than in the other groups (all p < 0.01). Conclusions: CONUT scores at admission are associated with functional recovery, mortality, and the incidence of complications following a first-ever ischemic stroke. Consequently, the early identification of patients at risk of malnutrition via CONUT scores can be crucial in enhancing patient assessment after an acute stroke.

引用

页数：15

共 45 条

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