The Barrier Properties of Biological Membranes Dictate How Cells Experience Oxidative Stress

被引：2
作者：
Imlay, James A. [1 ]
机构：
[1] Univ Illinois, Dept Microbiol, Urbana, IL 61820 USA
来源：
MOLECULAR MICROBIOLOGY | 2025年 / 123卷 / 05期
基金：
美国国家卫生研究院;
关键词：
hydrogen peroxide; obligate anaerobiosis; oxidative stress; superoxide; PERIPLASMIC SUPEROXIDE-DISMUTASE; OXYR TRANSCRIPTION FACTOR; HYDROGEN-PEROXIDE; ESCHERICHIA-COLI; OXYGEN PERMEABILITY; CYTOCHROME BD; SALMONELLA; ACTIVATION; REDUCTASE; BACTERIA;
D O I：
10.1111/mmi.15353
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Molecular oxygen, superoxide, and hydrogen peroxide are related oxidants that can each impair the growth of microorganisms. Strikingly, these species exhibit large differences in their abilities to cross biological membranes. This Perspective explains the basis of those differences, and it describes natural situations in which the permeability of membranes to oxidants determines the amount of stress that a bacterium experiences.
引用
收藏
页码：454 / 463
页数：10
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