How Epstein Barr Virus Causes Lymphomas

被引：0

作者：

Chiu, Ya-Fang ^{[1
,2
,3
,4
,5
]}

Ponlachantra, Khongpon ^{[6
]}

Sugden, Bill ^{[7
]}

机构：

[1] Chang Gung Univ, Dept Microbiol & Immunol, Taoyuan 33302, Taiwan

[2] Chang Gung Univ, Grad Inst Biomed Sci, Taoyuan 33302, Taiwan

[3] Chang Gung Univ, Res Ctr Emerging Viral Infect, Taoyuan 33302, Taiwan

[4] New Taipei Municipal Tucheng Hosp, Dept Med, Div Infect Dis, New Taipei City, Taiwan

[5] Chang Gung Mem Hosp, Dept Lab Med, Linkou 33305, Taiwan

[6] Vidyasirimedhi Inst Sci & Technol, Sch Biomol Sci & Engn, Rayong 21210, Thailand

[7] Univ Wisconsin Madison, McArdle Lab Canc Res, Madison, WI 53705 USA

来源：

VIRUSES-BASEL | 2024年 / 16卷 / 11期

基金：

美国国家卫生研究院;

关键词：

EBV; lymphomas; SARCOMA-ASSOCIATED HERPESVIRUS; MEMBRANE-PROTEIN; 2A; T-CELL RESPONSES; CENTER B-CELLS; BURKITTS-LYMPHOMA; GENE-EXPRESSION; SMALL RNAS; HUMAN-LEUKOCYTES; EBV PERSISTENCE; HOST-RANGE;

D O I：

10.3390/v16111744

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Since Epstein-Barr Virus (EBV) was isolated 60 years ago, it has been studied clinically, epidemiologically, immunologically, and molecularly in the ensuing years. These combined studies allow a broad mechanistic understanding of how this ubiquitous human pathogen which infects more than 90% of adults can rarely cause multiple types of lymphomas. We survey these findings to provide a coherent description of its oncogenesis.

引用

页数：16

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