How Epstein Barr Virus Causes Lymphomas

被引:0
|
作者
Chiu, Ya-Fang [1 ,2 ,3 ,4 ,5 ]
Ponlachantra, Khongpon [6 ]
Sugden, Bill [7 ]
机构
[1] Chang Gung Univ, Dept Microbiol & Immunol, Taoyuan 33302, Taiwan
[2] Chang Gung Univ, Grad Inst Biomed Sci, Taoyuan 33302, Taiwan
[3] Chang Gung Univ, Res Ctr Emerging Viral Infect, Taoyuan 33302, Taiwan
[4] New Taipei Municipal Tucheng Hosp, Dept Med, Div Infect Dis, New Taipei City, Taiwan
[5] Chang Gung Mem Hosp, Dept Lab Med, Linkou 33305, Taiwan
[6] Vidyasirimedhi Inst Sci & Technol, Sch Biomol Sci & Engn, Rayong 21210, Thailand
[7] Univ Wisconsin Madison, McArdle Lab Canc Res, Madison, WI 53705 USA
来源
VIRUSES-BASEL | 2024年 / 16卷 / 11期
基金
美国国家卫生研究院;
关键词
EBV; lymphomas; SARCOMA-ASSOCIATED HERPESVIRUS; MEMBRANE-PROTEIN; 2A; T-CELL RESPONSES; CENTER B-CELLS; BURKITTS-LYMPHOMA; GENE-EXPRESSION; SMALL RNAS; HUMAN-LEUKOCYTES; EBV PERSISTENCE; HOST-RANGE;
D O I
10.3390/v16111744
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Since Epstein-Barr Virus (EBV) was isolated 60 years ago, it has been studied clinically, epidemiologically, immunologically, and molecularly in the ensuing years. These combined studies allow a broad mechanistic understanding of how this ubiquitous human pathogen which infects more than 90% of adults can rarely cause multiple types of lymphomas. We survey these findings to provide a coherent description of its oncogenesis.
引用
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页数:16
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