Thyroid eye disease and ocular myasthenia gravis

被引:0
作者
Shabto, Julie M. [1 ]
Stevens, Shanlee [1 ]
Kazim, Michael [1 ]
机构
[1] Columbia Univ, Edward S Harkness Eye Inst, New York, NY USA
关键词
diplopia; disease modulation; myasthenia gravis; ocular motility disorder; thyroid eye disease; NATURAL-HISTORY; RECEPTOR; ANTIBODIES; THERAPY; RISK; OPHTHALMOPATHY; MANAGEMENT; PROGNOSIS; RITUXIMAB; EFFICACY;
D O I
10.1097/WCO.0000000000001339
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Purpose of reviewAn overview of two ocular diseases, which significantly impact quality of life: thyroid eye disease (TED) and ocular myasthenia gravis (OMG). Additionally, we describe the clinical challenge when they occur simultaneously. We will describe the pathophysiology of both conditions, the currently available diagnostic tools, and the therapies available.Recent findingsRecent literature has described newer diagnostic modalities, predictors of disease severity and co-occurrence of TED and OMG, and novel therapies. There is also critical analysis of current therapeutics and risk factors.SummaryThe findings from this review suggest a need for heightened clinical awareness and early detection strategies for TED and OMG due to their overlapping clinical presentation. Emerging therapies and diagnostic techniques should be integrated into practice. Further research is warranted to explore the long-term safety and efficacy of novel treatments and the potential genetic links between these conditions.
引用
收藏
页码:71 / 78
页数:8
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