Recognition of Idiopathic Inflammatory Myopathies Underlying Interstitial Lung Diseases

被引:2
作者
Morina, Giulia [1 ]
Sambataro, Domenico [2 ]
Libra, Alessandro [1 ]
Palmucci, Stefano [3 ]
Colaci, Michele [4 ]
La Rocca, Gaetano [5 ]
Ferro, Francesco [5 ]
Carli, Linda [5 ]
Baldini, Chiara [5 ]
Liuzzo, Santa Valentina [1 ]
Vancheri, Carlo [1 ]
Sambataro, Gianluca [6 ]
机构
[1] Univ Catania, Reg Referral Ctr Rare Lung Dis, Dept Clin & Expt Med, Policlin G Rodolico San Marco, I-95123 Catania, Italy
[2] Artroreuma SRL, Outpatient Clin Associated Reg Hlth Syst, I-95030 Catania, Italy
[3] Univ Catania, Univ Hosp Policlin G Rodolico San Marco, Dept Med Surg Sci & Adv Technol GF Ingrassia, Unita Operativa Semplice Dipartimentale Imaging Po, I-95123 Catania, Italy
[4] Univ Catania, Dept Clin & Expt Med, Div Rheumatol, Internal Med Unit,Cannizzaro Hosp, I-95123 Catania, Italy
[5] Univ Pisa, Dept Clin & Expt Med, Rheumatol Unit, I-56126 Pisa, Italy
[6] Univ Enna Kore, Dept Med & Surg, I-94100 Enna, Italy
关键词
interstitial lung disease; idiopathic inflammatory myopathies; dermatomyositis; polymyositis; antisynthetase syndrome; autoantibodies; CLASSIFICATION CRITERIA; PULMONARY-FUNCTION; AUTOANTIBODIES; MUSCLE; DERMATOMYOSITIS; POLYMYOSITIS; ANTIBODIES; MYOSITIS; ASSOCIATION; DIAGNOSIS;
D O I
10.3390/diagnostics15030275
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Interstitial Lung Disease (ILD) is one of the most common causes of mortality in idiopathic Inflammatory Myopathies (IIM). Despite these conditions being commonly associated with proximal weakness, skin rashes and arthritis, ILD can be the first or the sole clinical feature in up to 60% of patients, potentially leading to incorrect diagnosis. The early recognition of an underlying IIM in ILD patients can allow for prompt treatment, which could potentially stabilize or even improve the lung disease, also avoiding the development of other clinical features associated with the condition. The objective of this review is to describe the clinical, serological and radiological features associated with IIM-ILD, mainly focusing on dermatomyositis and antisynthetase syndrome.
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页数:16
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