Effects of acupuncture-related intervention on chemotherapy-induced peripheral neuropathy and quality of life: An umbrella review

被引：0
作者：
Yeh, Mei-Ling [1 ,2 ]
Hsu, Chin-Che [3 ]
Lin, Matthew [4 ]
Lin, Chuan-Ju [5 ,6 ]
Lin, Jaung-Geng [7 ]
机构：
[1] Natl Taipei Univ Nursing & Hlth Sci, Taipei Med Univ Res Ctr Cochrane Taiwan, Sch Nursing, Minte Rd, Taipei 365, Taiwan
[2] Taipei Med Univ Res Ctr Cochrane Taiwan, Taipei, Taiwan
[3] Kaohsiung Med Univ Hosp, 100 Tzyou 1st Rd, Kaohsiung, Taiwan
[4] Natl Taipei Univ Nursing & Hlth Sci, Sch Nursing, 365 Minte Rd, Taipei, Taiwan
[5] Hsinchu Cathay Gen Hosp, 678,Sect 2,Zhonghua Rd, Hsinchu, Taiwan
[6] Natl Taipei Univ Nursing & Hlth Sci, Taipei, Taiwan
[7] China Med Univ, Sch Chinese Med, 91 Hsueh Shih Rd, Taichung, Taiwan
来源：
COMPLEMENTARY THERAPIES IN MEDICINE | 2025年 / 89卷
关键词：
Acupuncture; Chemotherapy-induced peripheral neuropathy; Pain; Quality of life; Umbrella review; NONPHARMACOLOGICAL INTERVENTIONS;
D O I：
10.1016/j.ctim.2025.103131
中图分类号：
R [医药、卫生];
学科分类号：
10 ;
摘要：
Background: Numerous studies have explored the role of acupuncture-related treatments in alleviating chemotherapy-induced peripheral neuropathy (CIPN) and improving the quality of life for patients with cancer, resulting in mixed findings. This umbrella review aimed to synthesize existing systematic reviews (SRs) to deliver an updated assessment of the certainty of evidence concerning the effects of acupuncture-related treatments on CIPN and quality of life among a diverse group of patients with cancer. Methods: This umbrella review considered eligible SRs published on one of nine electronic databases between inception and August 2024. It included adult patients with cancer of any stage who were undergoing chemotherapy. Interventions encompassed acupuncture, either alone or with electrical stimulation or moxibustion, and transcutaneous electrical acupoint/nerve stimulation (TEAS). The outcomes analyzed were changes in CIPN, nerve conduction velocity (NCV), and quality of life. Results: The outcomes were evaluated using data obtained from 14 SRs that demonstrated moderate to high methodological and reporting quality. The findings showed that acupuncture (either alone or combined with electrical stimulation) and TEAS effectively alleviated CIPN symptoms, reduced CIPN pain, improved NCV, and enhanced quality of life. Conclusion: The findings of this umbrella review indicate that these benefits were usually noticeable by the second week of treatment, persisted until the sixth week, and then gradually declined. Sensory nerve recovery occurred more rapidly than motor nerve recovery, often within 1.5 weeks. Although acupuncture combined with moxibustion or acupressure also enhanced patient outcomes, there was insufficient information available for further study analysis.
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页数：11
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  • [1] Sreeram K., Seaton R., Greenwald M.K., Et al., Chemotherapy-induced peripheral neuropathy in the Detroit research on cancer survivors (ROCS) cohort, Cancer Causes Control, 34, 5, pp. 459-468, (2023)
  • [2] Ma J., Kavelaars A., Dougherty P.M., Heijnen C.J., Beyond symptomatic relief for chemotherapy-induced peripheral neuropathy: targeting the source, Cancer, 124, 11, pp. 2289-2298, (2018)
  • [3] Zajaczkowska R., Kocot-Kepska M., Leppert W., Et al., Mechanisms of cemotherapy-iduced pripheral neropathy, Int J Mol Sci, 20, 6, (2019)
  • [4] Colvin L.A., Chemotherapy-induced peripheral neuropathy: where are we now?, Pain, 160 Suppl 1, 160, 1, pp. S1-S10, (2019)
  • [5] Staff N.P., Grisold A., Grisold W., Et al., Chemotherapy-induced peripheral neuropathy: a current review, Ann Neurol, 81, 6, pp. 772-781, (2017)
  • [6] Ibrahim E.Y., Ehrlich B.E., Prevention of chemotherapy-induced peripheral neuropathy: a review of recent findings, Crit Rev Oncol Hematol, 145, (2020)
  • [7] Wiranata J.A., Astari Y.K., Ucche M., Et al., Predictive factors of chemotherapy-induced peripheral neuropathy in breast cancer: a decision tree model approach, JCO Glob Oncol, 10, (2024)
  • [8] Flatters S.J.L., Dougherty P.M., Colvin L.A., Clinical and preclinical perspectives on chemotherapy-induced peripheral neuropathy (CIPN): a narrative review, Br J Anaesth, 119, 4, pp. 737-749, (2017)
  • [9] Loprinzi C.L., Lacchetti C., Bleeker J., Et al., Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: ASCO guideline update, J Clin Oncol, 38, 28, pp. 3325-3348, (2020)
  • [10] Chow R., Novosel M., So O.W., Et al., Duloxetine for prevention and treatment of chemotherapy-induced peripheral neuropathy (CIPN): systematic review and meta-analysis, BMJ Support Palliate Care, 13, 1, pp. 27-34, (2023)
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