Primary pulmonary follicular lymphoma

Primary pulmonary follicular lymphoma is an extremely rare subset of extra-nodal non-Hodgkin's lymphoma. We present a successful work-up and surgical management of this disease entity. The patient is a 74-year-old man who presented with an enlarging ground glass opacity on his computed tomography scan. Percutaneous biopsy was not diagnostic for malignancy, but given the underlying malignant potential, he underwent definitive operative resection rather than additional invasive diagnostic testing. Our case highlights challenges in the management of nondiagnostic preliminary pathology as well as the role of a multidisciplinary approach to treatment of a rare lung pathology.