Highly efficient synthesis of furan-2-ylmethylboranes by a copper-catalyzed three-component cascade strategy

被引：0

作者：

Hang, Chengrui ^{[1
]}

Lu, Fei ^{[1
]}

Song, Daan ^{[1
]}

Wang, Guanghui ^{[1
]}

Zhao, Ximei ^{[1
]}

机构：

[1] Ludong Univ, Sch Chem & Mat Sci, Yantai 264025, Peoples R China

来源：

NEW JOURNAL OF CHEMISTRY | 2025年 / 49卷 / 08期

基金：

中国国家自然科学基金;

关键词：

BOND INSERTION REACTION; B-H INSERTION; HYDROGEN BONDS; BORANE ADDUCTS; CHEMISTRY; ALKYNES;

D O I：

10.1039/d4nj05074f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The copper-catalyzed three-component Knoevenagel condensation/enynone cyclization/B-H bond insertion cascade offers a concise and highly efficient one-step access to furan-2-ylmethylboranes. This protocol has broad substrate scope and good functional group compatibility. Its synthetic practicability is demonstrated by a large-scale experiment and the application to facile one-pot synthesis of masked boronic acids.

引用

页码：3006 / 3009

页数：4

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