The Effect of Cardiopulmonary Exercise Ability to Clinical Outcomes of Patients with Coronary Artery Disease Undergoing Percutaneous Coronary Intervention

Objective: To analyze the relationship between the cardiopulmonary function and prognosis of patients with coronary heart disease after percutaneous coronary intervention (PCI). Methods: A total of 153 patients with coronary heart disease who underwent PCI from January 2018 to April 2020 were enrolled in this study. Through careful assessment, cardiopulmonary exercise test (CPX) was performed 5 to 7 days after PCI. Patients were followed up every 3 months by outpatient examination or telephone visiting for 3 years after discharge. Clinical outcomes were followed up, including cardiac death, rehospitalization, heart failure, atrial fibrillation, stroke and transient ischemic attack. A single clinical event was defined as a poor prognosis and divided into a good prognosis group and a poor prognosis group according to the prognosis. By comparing the cardiorespiratory fitness (CRF) variables and clinical parameters, the variables that may affect the prognosis of patients were determined. Results: CRF decreased significantly in the poor prognosis group, and peak VO2, VO2/kg AT, PETCO2 and ODES decreased compared with the good prognosis group, and the differences were statistically significant. Heart rate reserve (HRR) increased in the poor prognosis group compared with the good prognosis group, and the difference was statistically significant. Among them, peak VO2 and acute myocardial infarction were independent risk factors for poor prognosis. Conclusion: Peak VO2 is an independent risk factor for the prognosis of cardiovascular disease after PCI for coronary heart disease.