New progress in imaging diagnosis and immunotherapy of breast cancer

被引:0
|
作者
He, Jie [1 ]
Liu, Nan [2 ]
Zhao, Li [3 ]
机构
[1] Zhejiang Univ, Sir Run Run Shaw Hosp, Dept Radiol, Sch Med, Hangzhou, Zhejiang, Peoples R China
[2] Zhejiang Univ, Sir Run Run Shaw Hosp, Dept Translat Med & Clin Res, Sch Med, Hangzhou, Zhejiang, Peoples R China
[3] Shaoxing Peoples Hosp, Dept Radiol, Shaoxing, Zhejiang, Peoples R China
来源
FRONTIERS IN IMMUNOLOGY | 2025年 / 16卷
关键词
breast cancer; PD-1; immune checkpoint; immunotherapy; radiotherapy; imaging diagnosis; INTRAVOXEL INCOHERENT MOTION; T-CELLS; NEOADJUVANT CHEMOTHERAPY; DIFFERENTIAL-DIAGNOSIS; TUMOR MICROENVIRONMENT; MR SPECTROSCOPY; ULTRASOUND; LESIONS; PEMBROLIZUMAB; ELASTOGRAPHY;
D O I
10.3389/fimmu.2025.1560257
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Breast cancer (BC) is a predominant malignancy among women globally, with its etiology remaining largely elusive. Diagnosis primarily relies on invasive histopathological methods, which are often limited by sample representation and processing time. Consequently, non-invasive imaging techniques such as mammography, ultrasound, and Magnetic Resonance Imaging (MRI) are indispensable for BC screening, diagnosis, staging, and treatment monitoring. Recent advancements in imaging technologies and artificial intelligence-driven radiomics have enhanced precision medicine by enabling early detection, accurate molecular subtyping, and personalized therapeutic strategies. Despite reductions in mortality through traditional treatments, challenges like tumor heterogeneity and therapeutic resistance persist. Immunotherapies, particularly PD-1/PD-L1 inhibitors, have emerged as promising alternatives. This review explores recent developments in BC imaging diagnostics and immunotherapeutic approaches, aiming to inform clinical practices and optimize therapeutic outcomes.
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页数:10
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