Impact of repeat testing in tuberculosis patients with a trace call on Xpert MTB/RIF Ultra: a retrospective cohort study

被引：0

作者：

Jha, Suyash ^{[1
]}

Gupta, Nitin ^{[2
]}

Kumar, Tirlangi Praveen ^{[2
]}

Chawla, Kiran ^{[3
]}

Shenoy, Vishnu P. ^{[3
]}

Varma, Muralidhar ^{[2
]}

Manu, Mohan K. ^{[1
]}

机构：

[1] Manipal Acad Higher Educ, Kasturba Med Coll, Dept Resp Med, Udupi 576104, Karnataka, India

[2] Manipal Acad Higher Educ, Kasturba Med Coll, Dept Infect Dis, Udupi 576104, Karnataka, India

[3] Manipal Acad Higher Educ, Kasturba Med Coll, Dept Microbiol, Udupi 576104, Karnataka, India

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 2025年 / 119卷 / 06期

关键词：

GeneXpert Ultra; rifampicin; susceptibility; trace; tuberculosis; MYCOBACTERIUM-TUBERCULOSIS;

D O I：

10.1093/trstmh/traf002

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Background This study aimed to see if rifampicin susceptibility can be determined on repeat sampling in pulmonary tuberculosis with a trace call on the first GeneXpert Ultra report.Methods This retrospective cohort study included adults with a GeneXpert Ultra trace call in the first respiratory sample from January 2021 to June 2024.Results Of the 27 patients with repeat sampling done after the initial trace call, rifampicin susceptibility could be determined in 37% (n=10) of patients.Conclusions Repeating GeneXpert Ultra testing in patients with an initial trace call is valuable for determining rifampicin susceptibility.

引用

页码：626 / 628

页数：3

共 5 条

[1] Xpert MTB/RIF Ultra assay for the detection of Mycobacterium tuberculosis in people with negative conventional Xpert MTB/RIF but chest imaging suggestive of tuberculosis in Dhaka, Bangladesh [J].

Biswas, Samanta ;

Uddin, Mohammad Khaja Mafij ;

Paul, Kishor Kumar ;

Ather, Md Fahim ;

Ahmed, Shahriar ;

Nasrin, Rumana ;

Kabir, Senjuti ;

Heysell, Scott K. ;

Banu, Sayera .

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2022, 114 :244-251

[2] Xpert MTB/RIF Ultra versus Xpert MTB/RIF for the diagnosis of tuberculous meningitis: a prospective, randomised, diagnostic accuracy study [J].

Donovan, Joseph ;

Do Dang Anh Thu ;

Nguyen Hoan Phu ;

Vu Thi Mong Dung ;

Tran Phu Quang ;

Ho Dang Trung Nghia ;

Pham Kieu Nguyet Oanh ;

Tran Bao Nhu ;

Nguyen Van Vinh Chau ;

Vu Thi Ngoc Ha ;

Vu Thi Ty Hang ;

Dong Huu Khanh Trinh ;

Geskus, Ronald B. ;

Le Van Tan ;

Nguyen Thuy Thuong Thuong ;

Thwaites, Guy E. .

LANCET INFECTIOUS DISEASES, 2020, 20 (03) :299-307

[3] Update on the diagnosis of tuberculosis [J].

Kontsevaya, Irina ;

Cabibbe, Andrea Maurizio ;

Cirillo, Daniela Maria ;

DiNardo, Andrew R. ;

Frahm, Nicole ;

Gillespie, Stephen H. ;

Holtzman, David ;

Meiwes, Lennard ;

Petruccioli, Elisa ;

Reimann, Maja ;

Ruhwald, Morten ;

Sabiiti, Wilber ;

Saluzzo, Francesca ;

Tagliani, Elisa ;

Goletti, Delia .

CLINICAL MICROBIOLOGY AND INFECTION, 2024, 30 (09) :1115-1122

[4]

Xie YL, 2024, LANCET MICROBE, V5, pe520, DOI 10.1016/S2666-5247(24)00001-6

[5] Xpert Ultra versus Xpert MTB/RIF for pulmonary tuberculosis and rifampicin resistance in adults with presumptive pulmonary tuberculosis [J].

Zifodya, Jerry S. ;

Kreniske, Jonah S. ;

Schiller, Ian ;

Kohli, Mikashmi ;

Dendukuri, Nandini ;

Schumacher, Samuel G. ;

Ochodo, Eleanor A. ;

Haraka, Frederick ;

Zwerling, Alice A. ;

Pai, Madhukar ;

Steingart, Karen R. ;

Horne, David J. .

COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2021, (02)

← 1 →