Trends in Hyperpolypharmacy Before and After Nursing Home Admission Among Older Adults in Ontario, Canada

被引：0

作者：

Maclagan, Laura C. ^{[1
]}

Emdin, Abby ^{[1
]}

Huang, Anjie ^{[1
]}

Campitelli, Michael A. ^{[1
]}

Tadrous, Mina ^{[1
,3
,4
]}

Iaboni, Andrea ^{[5
,6
]}

Viana, Luis ^{[7
]}

Maxwell, Colleen J. ^{[1
,8
]}

Bronskill, Susan E. ^{[1
,2
,4
,9
]}

机构：

[1] ICES, Toronto, ON, Canada

[2] Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada

[3] Univ Toronto, Leslie Dan Fac Pharm, Toronto, ON, Canada

[4] Womens Coll Res Inst, Toronto, ON, Canada

[5] Univ Toronto, Fac Med, Dept Psychiat, Toronto, ON, Canada

[6] Univ Hlth Network, KITE Toronto Rehabil Inst, Toronto, ON, Canada

[7] North West Telepharm Solut, Deep River, ON, Canada

[8] Univ Waterloo, Sch Pharm, Kitchener, ON, Canada

[9] Sunnybrook Res Inst, Toronto, ON, Canada

来源：

AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY | 2025年 / 33卷 / 03期

关键词：

Hyperpolypharmacy; Nursing home; Community; Older adults; Psychotropics; POLYPHARMACY;

D O I：

10.1016/j.jagp.2024.09.005

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Objectives: To examine trends in the prevalence of hyperpolypharmacy prior to and following nursing home admission in Ontario, Canada. Methods: We conducted a cohort study of adults aged 75+ years admitted to nursing homes between 2017 and 2020 using health administrative data (n = 61,470). The prevalence of hyperpolypharmacy (>= 10 dispensed drugs) was assessed quarterly from ten years prior to 1.5 years following admission. Results: Over ten years, the prevalence of hyperpolypharmacy increased from 4.4% to 12.0% (+0.2% per quarter, [p <0.001]) and further increased after admission (13.8%). Antidepressants (three-fold), antipsychotics (seven-fold) and cholinesterase inhibitors (14-fold) increased significantly over ten years prior to admission, while cardiovascular medications peaked 4 to 5 years prior to admission. Conclusions: While hyperpolypharmacy increased nearly three-fold in the ten years prior to nursing home admission, patterns varied by drug class. Increasing hyperpolypharmacy throughout the life course suggests opportunities exist for medication reconciliation in community and nursing home settings. (Am J Geriatr Psychiatry 2025; 33:315-321)

引用

页码：315 / 321

页数：7

共 14 条

[1] American Geriatrics Society 2019 Updated AGS Beers Criteria® for Potentially Inappropriate Medication Use in Older Adults [J].