Unusual paralytic shellfish poisoning toxins in Cayuga Lake, New York

被引：0
作者：
Smith, Zacharias J. [1 ,2 ]
Boyer, Gregory L. [1 ]
机构：
[1] ARS, USDA, Hydrol & Remote Sensing Lab, 10300 Baltimore Ave, Beltsville, MD 20705 USA
[2] SUNY, Coll Environm Sci & Forestry, Dept Chem, 1 Forestry Dr, Syracuse, NY 13210 USA
来源：
TOXICON | 2024年 / 252卷
基金：
美国国家科学基金会;
关键词：
Harmful algae; HABs; Cyanobacteria; Cyanotoxin; Paralytic shellfish poisoning toxins; Saxitoxins; PCOX; Cayuga lake; RECEPTOR-BINDING ASSAY; SAXITOXIN;
D O I：
10.1016/j.toxicon.2024.108165
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Cyanobacteria blooms were detected in 2017 and 2018 in Cayuga Lake, New York, with paralytic shellfish poisoning toxins (PSPTs) the primary toxin detected. Analysis of these samples by HPLC with chemical oxidation, receptor binding assay, ELISA, and LC-MS/MS confirmed the presence of PSPTs but each method gave highly unusual results based on the theory establishing each method. The structures of the toxins could not be identified and may be 'unusual' or unelucidated PSPTs.
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页数：5
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