Atypical Thyroid Stimulating Hormone Levels in Myxedema Coma Complicated by Severe Sepsis

被引:0
作者
Hasan, Nazmul [1 ]
Yang, Daniel [1 ]
Othman, Thaer [1 ]
Dai-Ju, Jenny [1 ]
机构
[1] UCI Med Ctr, Orange, CA 92868 USA
关键词
Myxedema; Myxedema coma; Hypothyroidism; TSH;
D O I
10.55729/2000-9666.1412
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Most cases of Myxedema Coma are associated with primary hypothyroidism characterized by significantly elevated thyroid stimulating hormone (TSH) levels. However, this case presents an atypical manifestation of myxedema coma with low TSH levels despite severe hypothyroidism. The rarity of this presentation lies in the absence of central lesions typically responsible for such TSH suppression. This highlights a critical consideration: the profound impact of severe sepsis on thyroid hormone regulation and the hypothalamus-pituitary-thyroid axis.
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页数:5
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