Advances in research on the impact of exosomal miRNAs on liver metastasis of colorectal cancer

被引：0

作者：

Zhong, Xuemei ^{[1
]}

Guo, Dan ^{[1
]}

机构：

[1] Shaoguan Univ, Med Coll, Shaoguan 512026, Peoples R China

来源：

ONCOLOGIE | 2025年 / 27卷 / 02期

关键词：

colorectal cancer; liver metastasis; exosomes; miRNA; biomarkers; MICRORNAS; BIOMARKERS; DELIVERY; MIR-122; BIOLOGY; CELLS; SERUM;

D O I：

10.1515/oncologie-2024-0571

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Colorectal cancer (CRC) is a prevalent malignancy, and its liver metastasis is a key factor leading to patient death. Research has shown that exosomal microRNA (miRNA) plays an important role as a mediator of communication between tumor cells and other cells in the growth, invasion, and metastasis of cancer cells. It also plays a critical role in the occurrence and development of CRC liver metastasis (CRC-LM). This article reviews the biological functions of exosomal miRNA and explores its significant involvement in the mechanism of CRC-LM. It also focuses on the latest progress of extracellular vesicle miRNA in the study of CRC-LM, providing new ideas and methods for future treatments.

引用

页码：205 / 217

页数：13

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