Focal Therapy for Prostate Cancer: Recent Advances and Insights

被引：2

作者：

Lasorsa, Francesco ^{[1
,2
]}

Biasatti, Arianna ^{[1
,3
]}

Orsini, Angelo ^{[1
,4
]}

Bignante, Gabriele ^{[1
,5
]}

Farah, Gabriana M. ^{[1
]}

Pandolfo, Savio Domenico ^{[6
,7
]}

Lambertini, Luca ^{[8
]}

Reddy, Deepika ^{[9
]}

Damiano, Rocco ^{[10
]}

Ditonno, Pasquale ^{[2
]}

Lucarelli, Giuseppe ^{[2
]}

Autorino, Riccardo ^{[1
]}

Vourganti, Srinivas ^{[1
]}

机构：

[1] Rush Univ, Dept Urol, Chicago, IL 60612 USA

[2] Univ Bari Aldo Moro, Dept Precis & Regenerat Med & Ionian Area Urol, Androl & Kidney Transplantat Unit, I-70121 Bari, Italy

[3] Univ Trieste, Dept Med Surg & Hlth Sci, Urol Clin, I-34127 Trieste, Italy

[4] Univ G dAnnunzio, Dept Med Oral & Biotechnol Sci, Urol Unit, I-66013 Chieti, Italy

[5] Univ Turin, San Luigi Gonzaga Hosp, Dept Oncol, Div Urol, I-10043 Turin, Italy

[6] Univ Aquila, Dept Urol, I-67100 Laquila, Italy

[7] Univ Naples Federico II, Dept Neurosci Sci Reprod & Odontostomatol, I-80138 Naples, Italy

[8] Univ Florence, Careggi Hosp, Dept Expt & Clin Med, I-50121 Florence, Italy

[9] NHS Imperial Coll London, London W2 1NY, England

[10] Magna Graecia Univ Catanzaro, Dept Urol, I-88100 Catanzaro, Italy

来源：

CURRENT ONCOLOGY | 2025年 / 32卷 / 01期

关键词：

prostate cancer; focal therapy; ablation; TARGETED PHOTODYNAMIC THERAPY; INTENSITY FOCUSED ULTRASOUND; IRREVERSIBLE ELECTROPORATION; ARTERY EMBOLIZATION; LASER-ABLATION; FOLLOW-UP; RADIOFREQUENCY; OUTCOMES; CRYOABLATION; MULTICENTER;

D O I：

10.3390/curroncol32010015

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Focal therapy has emerged as a balanced middle ground aiming to reduce overtreatment and the risk of progression, as well as patients' distress and anxiety. Focal therapy and partial gland ablation prioritize the precise elimination of the index lesion and a surrounding safety margin to optimize treatment outcomes and lower the risk of residual disease. The paradigm of whole-gland ablation has shifted towards more targeted approaches. Several treatment templates ranging from subtotal and hemiablation to "hockey-stick", quadrant, and even focal lesion ablation have emerged. Many types of energy may be utilized during focal treatment. First, focal therapy can be grossly classified into thermal vs. non-thermal energy. The aim of this non-systematic review is to offer a comprehensive analysis of recently available evidence on focal therapy for PCa.

引用

页数：12

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