Watch-and-wait approach versus adjuvant treatment after radical awake resection in selected adult-type grade 3 gliomas, isocitrate dehydrogenase mutant: A case-matched cohort

被引：0

作者：

Elia, Angela ^{[1
,2
,3
]}

Roux, Alexandre ^{[1
,2
,3
]}

Trancart, Benedicte ^{[1
,2
]}

Moiraghi, Alessandro ^{[1
,2
,3
]}

Seneca, Maimiti ^{[1
,2
]}

Dezamis, Edouard ^{[1
,2
]}

Varlet, Pascale ^{[2
,3
,4
]}

Chretien, Fabrice ^{[2
,3
,4
]}

Oppenheim, Catherine ^{[3
,5
]}

Zanello, Marc ^{[1
,3
]}

Pallud, Johan ^{[1
,3
]}

机构：

[1] St Anne Hosp, GHU Paris Psychiat & Neurosci, Dept Neurosurg, Paris, France

[2] Univ Paris Cite, Fac Med, Paris, France

[3] INSERM, U1266, IMA Brain, Ctr Psychiat & Neurosci, Paris, France

[4] Sainte Anne Hosp, Dept Neuropathol, GHU Paris Psychiat & Neurosci, Paris, France

[5] Sainte Anne Hosp, GHU Paris Psychiat & Neurosci, Dept Neuroradiol, Paris, France

来源：

NEURO-ONCOLOGY ADVANCES | 2024年 / 6卷 / 01期

关键词：

awake surgery; grade; 3; glioma; radiotherapy; survival; watch-and-wait; BIPOLAR ELECTROSTIMULATION; SURGICAL RESECTION; WHITE-MATTER; THERAPY; SURGERY; TUMORS;

D O I：

10.1093/noajnl/vdae189

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Gliomas are a type of brain tumor. Gliomas are graded between grades 2 and 4 by pathologists, with higher grades being more aggressive tumors. Some doctors recommend additional treatments like chemotherapy and radiation right after surgery, while others may not suggest any more immediate treatment for grade 3 gliomas. The authors of this study wanted to see which approach is better. To do this they reviewed the medical records of 106 patients with grade 3 gliomas some of whom received chemotherapy and/or radiation immediately after surgery and others who did not receive any immediate treatment after surgery. Their results showed that there was no difference in how long patients lived, regardless of the treatment they received immediately after surgery.

引用

页数：14