Luteolin mitigates doxorubicin-induced hepatotoxicity and neurotoxicity: modulating the liver–brain axis via IRE1α/GRP78/ATF6 endoplasmic reticulum stress pathways and miRNA-199a-5p expression

被引:0
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作者
Rasha D. Abdrabou [1 ]
Rania M. Salama [2 ]
Reem N. El-Naga [3 ]
Samar S. Azab [3 ]
机构
[1] Misr International University (MIU),Clinical Pharmacy Department, Faculty of Pharmacy
[2] Misr International University (MIU),Pharmacology and Toxicology Department, Faculty of Pharmacy
[3] Ain Shams University,Pharmacology and Toxicology Department, Faculty of Pharmacy
关键词
Doxorubicin; Luteolin; ER stress; MiR- 199a- 5p; Liver-brain axis; Chemobrain;
D O I
10.1186/s43094-025-00793-8
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