Predicting Malignancy in Adnexal Tumors With FAPI PET/CT and FDG PET/CT A Case Report on a Borderline Ovarian Tumor

被引：0
作者：
Umachanger, Janani Kantharooban [1 ,2 ]
Zacho, Helle Damgaard [1 ,2 ,3 ]
Sylvest, Camilla [4 ]
Frandsen, Anna Poulsgaard [5 ]
Bentestuen, Morten [1 ,2 ,3 ]
机构：
[1] Aalborg Univ Hosp, Dept Nucl Med, Hobrovej 18-22, DK-9000 Aalborg, Denmark
[2] Aalborg Univ Hosp, Clin Canc Res Ctr, Aalborg, Denmark
[3] Aalborg Univ, Dept Clin Med, Aalborg, Denmark
[4] Aalborg Univ Hosp, Dept Gynecol & Obstet, Aalborg, Denmark
[5] Aalborg Univ Hosp, Dept Pathol, Aalborg, Denmark
来源：
CLINICAL NUCLEAR MEDICINE | 2025年 / 50卷 / 02期
关键词：
FAPI; FDG; PET/CT; borderline ovarian tumor; ovarian cancer; SURVIVAL;
D O I：
10.1097/RLU.0000000000005537
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
A 54-year-old woman presented with a 55 x 64-mm tumor in the ovary with high [F-18]FDG uptake on [F-18]FDG PET/CT highly suggestive of ovarian cancer. Prior to surgery, the patient underwent [Ga-68]-Ga- fibroblast activation protein inhibitor (FAPI)-46 PET/CT, which revealed low [Ga-68]-Ga-FAPI-46 tumor uptake. Histopathology revealed a borderline ovarian tumor, which has low malignant potential and a 10-year survival rate greater than 93%. High [F-18]FDG uptake is considered a fair predictor of malignancy in adnexal tumors. The present case demonstrates the potential superiority of [Ga-68]-Ga-FAPI-46 PET/CT over [F-18]-FDG PET/CT in differentiating malignant adnexal tumors from borderline ovarian tumors.
引用
收藏
页码：e124 / e126
页数：3
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