Necrotizing Enterocolitis: A Current Understanding and Challenges for the Future

被引：0

作者：

De Bernardo, Giuseppe ^{[1
]}

Vecchione, Carolina ^{[2
]}

Langella, Carmen ^{[1
]}

Ziello, Carla ^{[2
]}

Parisi, Grazia ^{[2
]}

Giordano, Maurizio ^{[3
]}

Buonocore, Giuseppe ^{[4
]}

Perrone, Serafina ^{[5
]}

机构：

[1] Buon Consiglio Fatebenefratelli Hosp, Dept Woman & Child, Naples, Italy

[2] Univ Naples Federico II, Dept Translat Med Sci, Div Pediat, Naples, Italy

[3] Univ Naples Federico II, Dept Clin Med & Surg, Naples, Italy

[4] Univ Siena, Dept Mol & Dev Med, Siena, Italy

[5] Univ Parma, Pietro Barilla Childrens Hosp, Dept Med & Surg, Neonatol Unit, Parma, Italy

来源：

CURRENT PEDIATRIC REVIEWS | 2024年

关键词：

Preterm newborns; antibiotics; dysbiosis; low body weight; mother; metabolites; ultrasound; genetic predisposition; OXIDATIVE STRESS; PROBIOTICS;

D O I：

10.2174/0115733963318619240923062033

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

This perspective reviews the definition and current understanding of necrotizing enterocolitis and evaluates a future prevention approach to this multifactorial disease. An overview of the prevention approach in general is presented, where key aspects and emerging criticisms are identified. In addition, key elements of early diagnosis and treatment are presented, together with some of their challenges and ambiguities. Moreover, it concludes with emerging questions from the global community to reach a consensus on the definition, diagnosis, and management of necrotizing enterocolitis disease.

引用

页数：6

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