Necrotizing Enterocolitis: A Current Understanding and Challenges for the Future

被引:0
|
作者
De Bernardo, Giuseppe [1 ]
Vecchione, Carolina [2 ]
Langella, Carmen [1 ]
Ziello, Carla [2 ]
Parisi, Grazia [2 ]
Giordano, Maurizio [3 ]
Buonocore, Giuseppe [4 ]
Perrone, Serafina [5 ]
机构
[1] Buon Consiglio Fatebenefratelli Hosp, Dept Woman & Child, Naples, Italy
[2] Univ Naples Federico II, Dept Translat Med Sci, Div Pediat, Naples, Italy
[3] Univ Naples Federico II, Dept Clin Med & Surg, Naples, Italy
[4] Univ Siena, Dept Mol & Dev Med, Siena, Italy
[5] Univ Parma, Pietro Barilla Childrens Hosp, Dept Med & Surg, Neonatol Unit, Parma, Italy
关键词
Preterm newborns; antibiotics; dysbiosis; low body weight; mother; metabolites; ultrasound; genetic predisposition; OXIDATIVE STRESS; PROBIOTICS;
D O I
10.2174/0115733963318619240923062033
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
This perspective reviews the definition and current understanding of necrotizing enterocolitis and evaluates a future prevention approach to this multifactorial disease. An overview of the prevention approach in general is presented, where key aspects and emerging criticisms are identified. In addition, key elements of early diagnosis and treatment are presented, together with some of their challenges and ambiguities. Moreover, it concludes with emerging questions from the global community to reach a consensus on the definition, diagnosis, and management of necrotizing enterocolitis disease.
引用
收藏
页数:6
相关论文
共 50 条
  • [21] Probiotics and the mechanism of necrotizing enterocolitis
    Chen, Chien-Chang
    Walker, W. Allan
    SEMINARS IN PEDIATRIC SURGERY, 2013, 22 (02) : 94 - 100
  • [22] Treatment of Necrotizing Enterocolitis with Probiotics
    Ganguli, Kriston
    Walker, W. Allan
    GASTROENTEROLOGY CLINICS OF NORTH AMERICA, 2012, 41 (04) : 733 - +
  • [23] Antibiotic therapy and necrotizing enterocolitis
    Pace, Elizabeth
    Yanowitz, Toby D.
    Waltz, Paul
    Morowitz, Michael J.
    SEMINARS IN PEDIATRIC SURGERY, 2023, 32 (03)
  • [24] Necrotizing Enterocolitis: The Mystery Goes On
    Neu, Josef
    NEONATOLOGY, 2014, 106 (04) : 289 - 295
  • [25] The role of ultrasound in necrotizing enterocolitis
    Misun Hwang
    Luis O. Tierradentro-García
    Rebecca A. Dennis
    Sudha A. Anupindi
    Pediatric Radiology, 2022, 52 : 702 - 715
  • [26] New Strategies for Necrotizing Enterocolitis Diagnosis and Prevention in Newborns
    Perrone, Serafina
    Cremonini, Isabella
    Marinelli, Francesca
    Monaco, Sara
    Nicoletti, Laura
    Giordano, Maurizio
    Esposito, Susanna
    CURRENT PEDIATRIC REVIEWS, 2021, 17 (03) : 191 - 200
  • [27] The Risk of Developing Constipation After Neonatal Necrotizing Enterocolitis
    Chen, Shan-Ming
    Huang, Jing-Yang
    Wu, Ming-Chi
    Chen, Jia-Yuh
    FRONTIERS IN PEDIATRICS, 2020, 8
  • [28] Disruptions of the intestinal microbiome in necrotizing enterocolitis, short bowel syndrome, and Hirschsprung's associated enterocolitis
    Till, Holger
    Castellani, Christoph
    Moissl-Eichinger, Christine
    Gorkiewicz, Gregor
    Singer, Georg
    FRONTIERS IN MICROBIOLOGY, 2015, 6
  • [29] Adverse cardiovascular responses of engineered nanomaterials: Current understanding of molecular mechanisms and future challenges
    Alsaleh, Nasser B.
    NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2021, 37
  • [30] A Review of the Diagnosis and Treatment of Necrotizing Enterocolitis
    Cai, Xue
    Liebe, Heather L.
    Golubkova, Alena
    Leiva, Tyler
    Hunter, Catherine J.
    CURRENT PEDIATRIC REVIEWS, 2023, 19 (03) : 285 - 295