An epigenetic signature is associated with multiple sclerosis independently of known genetic risk and is a more accurate classifier

被引：0

作者：

Xavier, Alexandre ^{[1
]}

Maltby, Vicki E. ^{[2
,3
]}

Ewing, Ewoud ^{[4
]}

Campagna, Maria Pia ^{[5
]}

Burnard, Sean M. ^{[1
]}

Tegner, Jesper N. ^{[6
,7
,8
,9
]}

Slee, Mark ^{[10
]}

Butzkueven, Helmut ^{[5
,11
]}

Kockum, Ingrid ^{[4
]}

Kular, Lara ^{[4
]}

Jokubaitis, Vilija G.

Kilpatrick, Trevor

Alfredsson, Lars ^{[4
]}

Jagodic, Maja ^{[4
]}

Ponsonby, Anne-Louise ^{[12
,13
]}

Taylor, Bruce ^{[14
]}

Scott, Rodney J. ^{[1
,15
]}

Lea, Rodney A. ^{[2
,16
]}

Lechner-Scott, Jeannette ^{[2
,3
]}

机构：

[1] Univ Newcastle, Hunter Med Res Inst, Sch Biomed Sci & Pharm, Newcastle, NSW, Australia

[2] Univ Newcastle, Hunter Med Res Inst, Sch Med & Publ Hlth, Newcastle, NSW, Australia

[3] John Hunter Hosp, Dept Neurol, New Lambton Hts, NSW, Australia

[4] Karolinska Univ Hosp, Karolinska Inst, Dept Clin Neurosci, Ctr Mol Med, S-17176 Stockholm, Sweden

[5] Monash Univ, Dept Neurosci, Cent Clin Sch, Melbourne, Vic, Australia

[6] King Abdullah Univ Sci & Technol KAUST, Biol & Environm Sci & Engn Div, Thuwal 239556900, Saudi Arabia

[7] King Abdullah Univ Sci & Technol KAUST, Comp Elect & Math Sci & Engn Div, Thuwal 239556900, Saudi Arabia

[8] Karolinska Univ Hosp, Karolinska Inst, Dept Med, Unit Computat Med,L8 05, SE-17176 Stockholm, Sweden

[9] Sci Life Lab, Tomtebodavagen 23A, SE-17165 Solna, Sweden

[10] Flinders Univ S Australia, Coll Med & Publ Hlth, Adelaide, SA, Australia

[11] MSBase Fdn, Melbourne, Vic, Australia

[12] Univ Melbourne, Florey Inst Neurosci & Mental Hlth, Melbourne, Vic, Australia

[13] Australian Natl Univ, Natl Ctr Epidemiol & Publ Hlth, Canberra, ACT, Australia

[14] Univ Tasmania, Inst Med Res, Hobart, Tas, Australia

[15] John Hunter Hosp, Dept Mol Genet, Pathol North, New Lambton Hts, NSW, Australia

[16] Queensland Univ Technol, Sch Biomed Sci, Ctr Genom & Personalised Hlth, Kelvin Grove, Qld, Australia

来源：

MULTIPLE SCLEROSIS JOURNAL | 2024年 / 30卷 / 04期

关键词：

multiple sclerosis; methylation; HLA-DRB1*1501; classification; genetic risk;

D O I：

暂无

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

引用

页码：27 / 28

页数：2