A phase I/II study of davutamig (REGN5093), a METxMET bispecific antibody, in patients with MET-altered, advanced non-small cell lung cancer (aNSCLC): Trial in progress update

被引:0
|
作者
Ahn, M-j.
Cho, B. C. [1 ]
Kim, T. M. [2 ]
Han, J-y.
Kim, C. [3 ]
Shim, B. [4 ]
Drilon, A. [5 ,6 ]
Blumenschein, G. [7 ]
Villaruz, L. [8 ]
Gray, J. E. [9 ]
Pujol, J-l. [10 ]
Lena, H. [11 ]
Moro-Sibilot, D. [12 ]
Perez, J. [13 ]
Modi, D. A. [13 ]
Park, J. S. [13 ]
Patel, S. [13 ]
Li, S. [13 ]
Kim, E. [13 ]
Magnan, H. [13 ]
机构
[1] Yonsei Canc Ctr, Div Med Oncol, Seoul, South Korea
[2] Seoul Natl Univ Hosp, Internal Med, Seoul, South Korea
[3] Georgetown Univ, Med Oncol, Hematol Oncol, Washington, DC USA
[4] Catholic Univ Korea, Dept Med Oncol, Seoul, South Korea
[5] Weill Cornell Med Ctr, Mem Sloan Kettering Canc Ctr, New York, NY USA
[6] Weill Cornell Med Ctr, New York, NY USA
[7] Univ Texas MD Anderson Canc Ctr, Dept Thorac Head & Neck Med Oncol, Houston, TX USA
[8] Univ Pittsburgh Med Ctr UPMC, Hillman Canc Ctr, Dept Oncol, Pittsburgh, PA USA
[9] H Lee Moffitt Canc Ctr & Res Inst, Dept Oncol, Tampa, FL USA
[10] Ctr Hosp Reg Univ CHRU Montpellier Arnaud Villeneu, Dept Thorac & Vasc Surg, Montpellier, France
[11] Univ Rennes, Dept Oncol, Rennes, France
[12] Ctr Hosp Univ Grenoble, F-38000 Grenoble, France
[13] Regeneron Pharmaceut Inc, Med Oncol, Tarrytown, NY USA
关键词
D O I
10.1016/j.annonc.2024.10.754
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
721TiP
引用
收藏
页码:S1673 / S1674
页数:2
相关论文
共 50 条
  • [41] Weekly (W) cisplatin (P) and vinorelbine (V) in advanced non-small cell lung cancer (ANSCLC) elderly patients: A phase II study.
    Lippe, P
    Imperatori, L
    Casadei, V
    Guidi, F
    Gattafoni, P
    Consales, DL
    Mattioli, R
    ANNALS OF ONCOLOGY, 2000, 11 : 73 - 73
  • [42] Phase I/II trial on TS-1 monotherapy for aged patients with advanced non-small cell lung cancer
    Nanki, N.
    Ymaji, Y.
    Bandoh, S.
    Miyawaki, H.
    Ueda, Y.
    JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (15)
  • [43] A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer
    Michael A Morse
    Jennifer Garst
    Takuya Osada
    Shubi Khan
    Amy Hobeika
    Timothy M Clay
    Nancy Valente
    Revati Shreeniwas
    Mary Ann Sutton
    Alain Delcayre
    Di-Hwei Hsu
    Jean-Bernard Le Pecq
    H Kim Lyerly
    Journal of Translational Medicine, 3
  • [44] A phase I/II study of pemetrexed and vinorelbine in patients with non-small cell lung cancer
    Clarke, SJ
    Boyer, MJ
    Millward, M
    Underhill, C
    Moylan, E
    Yip, D
    White, S
    Childs, A
    Beale, P
    Latz, J
    Suri, A
    Iglesias, JL
    LUNG CANCER, 2005, 49 (03) : 401 - 412
  • [45] Phase II study of crizotinib in Japanese patients with advanced non-small cell lung cancer harboring a MET gene alteration: Co-MET study
    Shimokawa, M.
    Nosaki, K.
    Seto, T.
    Ohashi, K.
    Morise, M.
    Fujiwara, Y.
    Sakakibara, J.
    Murakami, H.
    Yano, S.
    Satouchi, M.
    Matsumoto, S.
    Goto, K.
    Yoh, K.
    ANNALS OF ONCOLOGY, 2019, 30
  • [46] A phase I study of CKD-702, an EGFR-cMET bispecific antibody, in advanced or metastatic non-small cell lung cancer (NSCLC)
    Kim, D-W.
    Lee, S-H.
    Jang, I-J.
    Park, K-J.
    Lee, D. H.
    ANNALS OF ONCOLOGY, 2022, 33 (07) : S1010 - S1010
  • [47] Phase II trial of docetaxel (D) plus gefitinib (G) in elderly (≥70 years) patients with advanced stage non-small cell lung cancer (ANSCLC)
    Williams, C.
    Bepler, G.
    Begum, M.
    Chiappori, A.
    Arora, R.
    Haura, E.
    Antonia, S.
    Extermann, M.
    Simon, G.
    JOURNAL OF CLINICAL ONCOLOGY, 2007, 25 (18)
  • [48] A phase II trial of biweekly docetaxel combined with carboplatin for patients with advanced non-small cell lung cancer
    Ishimoto, O
    Sugawara, S
    Inoue, A
    Ishida, T
    Koinumaru, S
    Hasegawa, Y
    Suzuki, T
    Miki, H
    Saijo, Y
    Nukiwa, T
    LUNG CANCER, 2005, 49 : S391 - S391
  • [49] A Phase II Trial of Denileukin Diftitox in Patients With Previously Treated Advanced Non-Small Cell Lung Cancer
    Gerena-Lewis, Margie
    Crawford, Jeffrey
    Bonomi, Philip
    Maddox, Ann Marie
    Hainsworth, John
    McCune, David E.
    Shukla, Rakesh
    Zeigler, Haoyue
    Hurtubise, Paul
    Chowdhury, Tracy R.
    Fletcher, Brandon
    Dyehouse, Karyn
    Ghalie, Richard
    Jazieh, Abdul R.
    AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 2009, 32 (03): : 269 - 273
  • [50] Phase II Trial of Thalidomide, Irinotecan and Gemcitabine in Chemonaive Patients with Advanced Non-Small Cell Lung Cancer
    Jazieh, A. R.
    Komrokji, R.
    Gupta, A.
    Patil, S.
    Flora, D.
    Knapp, M.
    Issa, M.
    Karim, N. Abdel
    CANCER INVESTIGATION, 2009, 27 (09) : 932 - 936