A phase I/II study of davutamig (REGN5093), a METxMET bispecific antibody, in patients with MET-altered, advanced non-small cell lung cancer (aNSCLC): Trial in progress update

被引：0
|
作者：
Ahn, M-j.
Cho, B. C. [1 ]
Kim, T. M. [2 ]
Han, J-y.
Kim, C. [3 ]
Shim, B. [4 ]
Drilon, A. [5 ,6 ]
Blumenschein, G. [7 ]
Villaruz, L. [8 ]
Gray, J. E. [9 ]
Pujol, J-l. [10 ]
Lena, H. [11 ]
Moro-Sibilot, D. [12 ]
Perez, J. [13 ]
Modi, D. A. [13 ]
Park, J. S. [13 ]
Patel, S. [13 ]
Li, S. [13 ]
Kim, E. [13 ]
Magnan, H. [13 ]
机构：
[1] Yonsei Canc Ctr, Div Med Oncol, Seoul, South Korea
[2] Seoul Natl Univ Hosp, Internal Med, Seoul, South Korea
[3] Georgetown Univ, Med Oncol, Hematol Oncol, Washington, DC USA
[4] Catholic Univ Korea, Dept Med Oncol, Seoul, South Korea
[5] Weill Cornell Med Ctr, Mem Sloan Kettering Canc Ctr, New York, NY USA
[6] Weill Cornell Med Ctr, New York, NY USA
[7] Univ Texas MD Anderson Canc Ctr, Dept Thorac Head & Neck Med Oncol, Houston, TX USA
[8] Univ Pittsburgh Med Ctr UPMC, Hillman Canc Ctr, Dept Oncol, Pittsburgh, PA USA
[9] H Lee Moffitt Canc Ctr & Res Inst, Dept Oncol, Tampa, FL USA
[10] Ctr Hosp Reg Univ CHRU Montpellier Arnaud Villeneu, Dept Thorac & Vasc Surg, Montpellier, France
[11] Univ Rennes, Dept Oncol, Rennes, France
[12] Ctr Hosp Univ Grenoble, F-38000 Grenoble, France
[13] Regeneron Pharmaceut Inc, Med Oncol, Tarrytown, NY USA
来源：
ANNALS OF ONCOLOGY | 2024年 / 35卷
关键词：
D O I：
10.1016/j.annonc.2024.10.754
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
721TiP
引用
收藏
页码：S1673 / S1674
页数：2
相关论文
共 50 条
  • [31] Phase II study of irinotecan and ifosfamide in patients with advanced non-small cell lung cancer
    Ichiki, M
    Rikimaru, T
    Gohara, R
    Koga, T
    Kawayama, T
    Matunami, M
    Oshita, Y
    Kamimura, T
    Aizawa, H
    ONCOLOGY, 2003, 64 (04) : 306 - 311
  • [32] A phase I/II trial of pemetrexed plus radiotherapy in elderly patients with locally advanced non-small cell lung cancer
    Tamiya, Akihiro
    Morimoto, Masahiro
    Fukuda, Shoichi
    Naoki, Yoko
    Ibe, Tatsuya
    Okishio, Kyoichi
    Goto, Hideto
    Yoshii, Akihiro
    Kita, Toshiyuki
    Nogami, Naoyuki
    Fujita, Yuka
    Atagi, Shinji
    INVESTIGATIONAL NEW DRUGS, 2018, 36 (04) : 667 - 673
  • [33] Phase I/II trial of dasatinib and osimertinib in patients with advanced EGFR-mutant non-small cell lung cancer
    Kim, Chul
    Liu, Stephen V.
    Subramaniam, Deepa Suresh
    Giaccone, Giuseppe
    JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (15)
  • [34] A phase I/II trial of cisplatin, docetaxel and ifosfamide in advanced or recurrent non-small cell lung cancer
    Kunitoh, H
    Akiyama, Y
    Kusaba, H
    Yamamoto, N
    Sekine, I
    Ohe, Y
    Kubota, K
    Tamura, T
    Shinkai, T
    Kodama, T
    Goto, K
    Niho, S
    Nishiwaki, Y
    Saijo, N
    LUNG CANCER, 2001, 33 (2-3) : 259 - 265
  • [35] A phase I/II trial of pemetrexed plus radiotherapy in elderly patients with locally advanced non-small cell lung cancer
    Akihiro Tamiya
    Masahiro Morimoto
    Shoichi Fukuda
    Yoko Naoki
    Tatsuya Ibe
    Kyoichi Okishio
    Hideto Goto
    Akihiro Yoshii
    Toshiyuki Kita
    Naoyuki Nogami
    Yuka Fujita
    Shinji Atagi
    Investigational New Drugs, 2018, 36 : 667 - 673
  • [36] Phase I/II trial of weekly docetaxel and carboplatin in previously untreated patients with advanced non-small cell lung cancer
    Walsh, W
    Gordon, J
    Merolli, R
    Seidler, C
    Kasturi, V
    Finn, T
    Liu, Q
    Strauss, G
    LUNG CANCER, 2004, 46 : S63 - S63
  • [37] Phase I/II study of amrubicin and nedaplatin in patients with untreated, advanced non-small cell lung cancer.
    Senju, Hiroaki
    Ogawara, Daiki
    Nakamura, Yoichi
    Fukuda, Minoru
    Nakatomi, Katsumi
    Gyotoku, Hiroshi
    Nakano, Hirofumi
    Yamaguchi, Hiroyuki
    Tomonaga, Nanae
    Ikeda, Takaya
    Mizoguchi, Kosuke
    Motoshima, Kohei
    Doi, Seiji
    Tsukamoto, Kazuhiro
    Kohno, Shigeru
    JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (15)
  • [38] Phase I/II trial of low dose cyclosporin A with EP for advanced non-small cell lung cancer
    Ross, HJ
    Cho, J
    Osann, K
    Wong, SF
    Ramsinghani, N
    Williams, J
    DowneyHurtado, N
    Slater, LM
    LUNG CANCER, 1997, 18 (02) : 189 - 198
  • [39] PHASE-II TRIAL OF ESORUBICIN IN PATIENTS WITH ADVANCED NON-SMALL CELL LUNG-CANCER
    KRIS, MG
    GRALLA, RJ
    BURKE, MT
    FIORE, JJ
    KELSEN, DP
    MARKS, LD
    HEELAN, RT
    CANCER TREATMENT REPORTS, 1987, 71 (7-8): : 783 - 784
  • [40] Phase I/II study of exisulind and gemcitabine in patients with recurrent advanced non-small cell lung cancer (NSCLC).
    Hoang, T
    Kim, K
    Merchant, J
    Traynor, AM
    Ahuja, HG
    Masters, GA
    McGovern, JD
    Oettel, KR
    Sanchez, FA
    Schiller, JH
    JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (14) : 642S - 642S
12345